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Novel and Innovative Hybrid Technique for Type A Aortic Dissection
Published on: March 28, 2025
Treatment of coronary malperfusion in type A acute aortic dissection
Keiji Uchida1, Norihisa Karube2, Tomoyuki Minami2
1Cardiovascular Center, Yokohama City University Medical Center, 4-57 Urafune-cho, Minami-ku, Yokohama, 232-0024, Japan. k_uchida@yokohama-cu.ac.jp.
Insights
Urgent percutaneous coronary intervention (PCI) can prevent acute myocardial infarction in acute aortic dissection patients. Prompt PCI for left coronary malperfusion improves cardiac function, outweighing tamponade risks.
Area of Science:
- Cardiovascular Surgery
- Interventional Cardiology
- Acute Aortic Syndromes
Background:
- Coronary malperfusion is a severe complication of acute aortic dissection, often leading to acute myocardial infarction.
- Patients with acute aortic dissection are critically ill, and coronary malperfusion exacerbates their condition.
Purpose of the Study:
- To outline a strategy for managing coronary malperfusion in acute aortic dissection.
- To evaluate the role and timing of percutaneous coronary intervention (PCI) before central repair surgery.
Main Methods:
- Immediate administration of heparin followed by emergency percutaneous coronary intervention (PCI).
- Stent placement covering the entire length of the dissected coronary artery.
- Assessment of cardiac function post-reperfusion to guide further surgical management.
Main Results:
- Successful coronary artery reperfusion via PCI improved cardiac function in some patients, allowing subsequent central repair.
- Patients requiring extracorporeal membrane oxygenation post-PCI without cardiac function recovery were managed with supportive care.
- Preoperative PCI for left coronary malperfusion is recommended due to its benefits in preserving cardiac function, despite potential risks.
Conclusions:
- Immediate preoperative PCI is crucial for left coronary malperfusion in acute aortic dissection to preserve cardiac function.
- PCI decisions for right coronary malperfusion require individualized assessment of patient condition and resource availability.
Abstract:
Coronary malperfusion is one of the most dreadful complications of acute aortic dissection because it causes catastrophic acute myocardial infarction in patients who are already severely ill. Our strategy was as follows. After the administration of heparin, emergency percutaneous coronary intervention (PCI) was urgently performed at the same time as starting to prepare the operating room. A stent was then placed to cover the full length of dissected coronary artery. Patients whose cardiac function improved after successful coronary artery reperfusion were transferred to the operating room to undergo central repair surgery. If the cardiac function did not recover even after coronary reperfusion, and the patient required extracorporeal membrane oxygenation, we considered the best supportive care without performing central repair surgery. In patients with left coronary malperfusion, we believe that preoperative PCI must be performed immediately. Preoperative PCI might delay central repair surgery and potentially increase the risk of catastrophic cardiac tamponade. However, the benefit of PCI in preserving cardiac function exceeds the risk of cardiac tamponade. The indications of PCI before central repair in patients with right coronary malperfusion should be considered after assessing each patient's condition, including the presence or absence of cardiac tamponade and right ventricular infarction, left ventricular function, the immediate availability of cardiologists or cardiac surgeons, and the speed of preparing the operating room.
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