Treatment of coronary malperfusion in type A acute aortic dissection

Keiji Uchida1, Norihisa Karube2, Tomoyuki Minami2

  • 1Cardiovascular Center, Yokohama City University Medical Center, 4-57 Urafune-cho, Minami-ku, Yokohama, 232-0024, Japan. k_uchida@yokohama-cu.ac.jp.

Insights

Urgent percutaneous coronary intervention (PCI) can prevent acute myocardial infarction in acute aortic dissection patients. Prompt PCI for left coronary malperfusion improves cardiac function, outweighing tamponade risks.

Area of Science:

  • Cardiovascular Surgery
  • Interventional Cardiology
  • Acute Aortic Syndromes

Background:

  • Coronary malperfusion is a severe complication of acute aortic dissection, often leading to acute myocardial infarction.
  • Patients with acute aortic dissection are critically ill, and coronary malperfusion exacerbates their condition.

Purpose of the Study:

  • To outline a strategy for managing coronary malperfusion in acute aortic dissection.
  • To evaluate the role and timing of percutaneous coronary intervention (PCI) before central repair surgery.

Main Methods:

  • Immediate administration of heparin followed by emergency percutaneous coronary intervention (PCI).
  • Stent placement covering the entire length of the dissected coronary artery.
  • Assessment of cardiac function post-reperfusion to guide further surgical management.

Main Results:

  • Successful coronary artery reperfusion via PCI improved cardiac function in some patients, allowing subsequent central repair.
  • Patients requiring extracorporeal membrane oxygenation post-PCI without cardiac function recovery were managed with supportive care.
  • Preoperative PCI for left coronary malperfusion is recommended due to its benefits in preserving cardiac function, despite potential risks.

Conclusions:

  • Immediate preoperative PCI is crucial for left coronary malperfusion in acute aortic dissection to preserve cardiac function.
  • PCI decisions for right coronary malperfusion require individualized assessment of patient condition and resource availability.

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