Related Experiment Video

Updated: Feb 5, 2026

Meta-Analysis of the Effectiveness and Safety of Shugan Jieyu Capsules for the Treatment of Insomnia
04:34

Meta-Analysis of the Effectiveness and Safety of Shugan Jieyu Capsules for the Treatment of Insomnia

Published on: February 17, 2023

1.6K

Does Mechanical Bowel Preparation Reduce the Risk of Developing Infectious Complications in Pediatric Colorectal

Koen Zwart1, Dirk-Jan Van Ginkel1, Caroline C C Hulsker1

  • 1Department of Pediatric Surgery, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.

The Journal of Pediatrics
|September 17, 2018
PubMed
Abstract

Insights

Mechanical bowel preparation (MBP) does not significantly reduce infectious complications in pediatric colorectal surgery. This systematic review found no evidence that MBP impacts wound infections or anastomotic leaks in children undergoing these procedures.

Area of Science:

  • Pediatric Surgery
  • Gastroenterology
  • Surgical Complications

Background:

  • Infectious complications are a concern following pediatric colorectal surgery.
  • Mechanical bowel preparation (MBP) is sometimes used to reduce these risks.
  • Evidence supporting MBP's efficacy in children is limited.

Purpose of the Study:

  • To evaluate the effectiveness of mechanical bowel preparation (MBP) in reducing infectious complications in pediatric patients undergoing colorectal surgery.
  • To synthesize current evidence on MBP's impact on surgical site infections and anastomotic leaks in children.

Main Methods:

  • Systematic review and meta-analysis of published studies.
  • Searched PubMed, Embase, and Cochrane Library for relevant pediatric colorectal surgery trials.
  • Compared outcomes between patients receiving MBP and those not receiving MBP.

Main Results:

  • Six studies involving 1977 pediatric patients (810 with MBP, 1167 without) were analyzed.
  • Overall infectious complications: 10.1% with MBP vs. 9.1% without (Risk Difference: -0.03%, 95% CI -0.09% to 0.03%).
  • No significant differences observed for wound infections or anastomotic leaks.

Conclusions:

  • Current evidence is insufficient to support the routine use of mechanical bowel preparation in pediatric colorectal surgery.
  • MBP does not appear to significantly alter the risk of infectious complications in this patient population.
  • Further research may be needed to clarify MBP's role, if any.
Keywords:
anastomotic leakagecolorectal surgeryinfectious complicationsmechanical bowel preparationmeta-analysispediatric surgerysystematic reviewwound infection

More Related Videos

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery06:46

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery

Published on: September 27, 2024

918
Povidone Iodine Rectal Preparation at Time of Prostate Needle Biopsy is a Simple and Reproducible Means to Reduce Risk of Procedural Infection05:32

Povidone Iodine Rectal Preparation at Time of Prostate Needle Biopsy is a Simple and Reproducible Means to Reduce Risk of Procedural Infection

Published on: September 21, 2015

33.9K

Related Concept Videos

Review and Preview01:10

Review and Preview

In statistics, several tools are used to interpret the data. Measures of central tendency represent the characteristics of the data, such as mean, median, and mode. Additionally, measures of variance like standard deviation and range are used to find the spread of data from the mean. Relative standing measures the distance between data locations. Commonly used measures of relative standings are percentile, z score, and quartiles.
Percentiles are a type of fractile that partition data into...
8.4K
Review and Preview01:13

Review and Preview

Data are individual items of information obtained from a population or sample. Data may be classified as qualitative (categorical), quantitative continuous, or quantitative discrete. Because it is not practical to measure the entire population in a study, researchers use samples to represent the population. A random sample is a representative group from the population chosen by using a method that gives each individual in the population an equal chance of being included in the sample. Random...
11.4K
Hemodialysis II: Procedure and Complications01:24

Hemodialysis II: Procedure and Complications

DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...
844
Random and Systematic Errors01:20

Random and Systematic Errors

Scientists always try their best to record measurements with the utmost accuracy and precision. However, sometimes errors do occur. These errors can be random or systematic. Random errors are observed due to the inconsistency or fluctuation in the measurement process, or variations in the quantity itself that is being measured. Such errors fluctuate from being greater than or less than the true value in repeated measurements. Consider a scientist measuring the length of an earthworm using a...
15.1K
Directing Effect of Substituents: meta-Directing Groups01:09

Directing Effect of Substituents: meta-Directing Groups

Substituents on the benzene ring that direct an incoming electrophile to undergo substitution at the meta position are called meta directors. All meta directors either have a positive charge on the atom directly bonded to the ring or a partial positive charge. These groups function by withdrawing electrons from the ring through inductive and resonance effects. Consider the carbocation intermediates formed upon the addition of an electrophile on nitrobenzene at the...
6.0K
Relative Risk01:12

Relative Risk

Relative risk (RR) is a statistical measure commonly used in epidemiology to compare the likelihood of a particular event occurring between two groups. This metric is important for evaluating the relationship between exposure to a specific risk factor and the probability of a particular outcome. It plays a crucial role in medical research, public health studies, and risk assessment. Relative risk quantifies how much more (or less) likely an event is to occur in an exposed group compared to an...
2.2K