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Automated ASPECT rating: comparison between the Frontier ASPECT Score software and the Brainomix software
Juliane Goebel1, Elena Stenzel2, Nika Guberina2
1Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Essen, Germany. Juliane.Goebel@uk-essen.de.
Neuroradiology
|September 17, 2018
Summary
Brainomix demonstrated high agreement in ASPECTS rating for acute ischemic stroke detection on CT scans, outperforming the Frontier system. This suggests Brainomix is a more reliable computer-aided diagnosis tool for early ischemic change assessment.
Area of Science:
- Neuroradiology
- Medical Imaging Analysis
- Artificial Intelligence in Medicine
Background:
- Early detection of ischemic changes on computed tomography (CT) is crucial for acute ischemic stroke management.
- Computer-aided diagnosis (CAD) systems show potential for improving the accuracy and efficiency of interpreting these changes.
Purpose of the Study:
- To compare the performance of two novel CAD systems, Frontier ASPECTS Prototype and Brainomix, against experienced human readers for detecting early ischemic changes.
- To evaluate the accuracy of ASPECTS (Alberta Stroke Program Early CT Score) ratings generated by these CAD systems in patients with suspected acute ischemic stroke.
Main Methods:
- Retrospective analysis of non-contrast brain CT scans from 150 patients with suspected middle cerebral artery ischemia.
- ASPECTS scoring was performed by two senior radiologists (consensus and individually) and by the Frontier and Brainomix CAD systems.
- Readings included fully automatic assessments and those adjusted for the affected brain side; statistical analysis used intraclass correlation and Bland-Altman methods.
Main Results:
- Brainomix demonstrated high correlation (r=0.714 to 0.841) with radiologists and expert consensus for score-based ASPECTS.
- Frontier showed only low to moderate correlation (r=0.471 to 0.680) with human readers and Brainomix.
- Bland-Altman analysis indicated better agreement for Brainomix (mean difference=-0.2, SD=1.15) compared to Frontier (mean difference=1.2, SD=1.76) when adjusted for brain side.
Conclusions:
- High agreement was observed between human readers, expert consensus, and the Brainomix CAD system for ASPECTS rating.
- The Frontier CAD system exhibited only low to moderate agreement with human readers and Brainomix.
- Brainomix shows greater promise as a reliable tool for computer-aided assessment of early ischemic changes in stroke patients.
Keywords:
ASPECTSArtificial intelligenceBrain computed tomographyComputer-aided diagnosisEarly ischemic change detectionMore Related Videos
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