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Updated: Feb 5, 2026

Use of a Linear Accelerator for Conducting In Vitro Radiobiology Experiments
Published on: May 26, 2019
Technical Note: Characterization of clinical linear accelerator triggering latency for motion management system
Andrew J Shepard1, Charles K Matrosic1, Jeffrey L Radtke1
1Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.
This study quantifies linear accelerator (linac) triggering latency, revealing it
Area of Science:
- Medical Physics
- Radiation Oncology
- Image-Guided Radiation Therapy
Background:
- Motion management systems in radiation therapy require precise timing for data acquisition, processing, and linac triggering.
- Existing latency guidelines often treat clinical linear accelerator (linac) triggering time as a fixed parameter.
- Decoupling linac-specific latency is crucial for accurately assessing and optimizing overall system performance.
Purpose of the Study:
- To develop a method for separating linac-only triggering latency from total system latency.
- To analyze the impact of accelerator settings on linac triggering latency.
- To enable latency considerations focused on linac-independent system components.
Main Methods:
- Measured linac-only triggering latency by comparing beam-on/off signal times with observed linac response.
- Utilized a multichannel oscilloscope, custom gating box, and in-isocenter diode for precise timing analysis.
- Investigated latency dependencies across various energies (6/18 MV) and repetition rates (100-600 MU/min).
Main Results:
- Linac triggering latency is dependent on accelerator repetition rate and energy settings.
- Beam-on latency decreased with higher repetition rates and lower energies; beam-off latency showed inverse trends.
- Observed latencies ranged from 3.37/1.45 ms (6 MV) to 6.02/0.73 ms (18 MV) at 600 MU/min; negative latencies were noted.
Conclusions:
- Linac triggering latency contributes minimally to the total allowable latency in motion management systems.
- The majority of system latency is attributable to linac-independent factors.
- This decoupling allows for more focused optimization of linac-independent system components.
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