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In 1928, a German botanist Emil Heitz observed the moss nuclei with a DNA binding dye. He observed that while some chromatin regions decondense and spread out in the interphase nucleus, others do not. He termed them euchromatin and heterochromatin, respectively. He proposed that the heterochromatin regions reflect a functionally inactive state of the genome. It was later confirmed that heterochromatin is transcriptionally repressed, and euchromatin is transcriptionally active chromatin.
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In anatomy, several standard anatomical positions are used as references for describing the position and orientation of different body parts. These positions help provide a common frame of reference when discussing anatomical structures. The anatomical position is the standard reference point for describing the body's position and orientation. In this position:
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Benign paroxysmal positional vertigo in children.

Qingxiu Yao1, Qiang Song1, Hui Wang1

  • 1Department of Otolaryngology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.

Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery
|September 17, 2018
PubMed
Summary
This summary is machine-generated.

Benign paroxysmal positional vertigo (BPPV) in children presents with specific clinical features and can be accurately diagnosed using positional testing. Pediatric BPPV is effectively treated with particle repositioning maneuvers, leading to rapid symptom resolution.

Keywords:
benign paroxysmal positional vertigochilddiagnosisdizzinessnystagmustreatmentvertigo

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Area of Science:

  • Pediatric Otolaryngology
  • Neurology
  • Vestibular Disorders

Background:

  • Benign paroxysmal positional vertigo (BPPV) is a common cause of vertigo, typically affecting adults.
  • The clinical presentation and management of BPPV in children are less well-documented compared to adults.

Purpose of the Study:

  • To describe the clinical features of BPPV in pediatric patients.
  • To evaluate the diagnostic accuracy and treatment efficacy of particle repositioning maneuvers for childhood BPPV.

Main Methods:

  • A retrospective study evaluating six children diagnosed with BPPV between March 2014 and March 2015.
  • Diagnosis was confirmed using the Dix-Hallpike and supine roll tests.
  • Treatment involved modified Epley, Lempert, or Gufoni particle repositioning procedures, with follow-up at 1-week intervals.

Main Results:

  • Four children had posterior canal BPPV, and two had horizontal canal BPPV.
  • Potential contributing factors included head trauma (1), family history of vertigo (1), and hearing loss (1).
  • 83.33% of children experienced complete vertigo relief after one treatment session, with the remaining child symptom-free after two sessions. No relapses were reported during follow-up (10-22 months).

Conclusions:

  • BPPV in children can be accurately diagnosed through detailed medical history and positional testing.
  • Particle repositioning maneuvers are effective and successful treatments for pediatric BPPV, leading to rapid symptom resolution and no reported relapses.