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A hybrid approach for patent ductus arteriosus closure using the Amplatzer Duct Occluder

Qun Gu1, Luyao Ma1, Haitao Gu1

  • 1Department of Cardiovascular Surgery, The First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu Province, China.

Journal of Cardiac Surgery
|September 18, 2018
PubMed

Insights

A novel hybrid approach successfully closed the patent ductus arteriosus (PDA) in infants using an Amplatzer Duct Occluder. This minimally invasive technique proved safe and effective, with no residual shunts observed post-procedure.

Area of Science:

  • Cardiovascular Surgery
  • Pediatric Cardiology
  • Medical Devices

Background:

  • Patent ductus arteriosus (PDA) is a common congenital heart defect in neonates and infants.
  • Traditional surgical closure can be invasive.
  • Minimally invasive techniques are sought for PDA treatment.

Purpose of the Study:

  • To evaluate the safety and efficacy of a novel hybrid approach for PDA closure.
  • To assess the use of an Amplatzer Duct Occluder in this hybrid procedure.

Main Methods:

  • A hybrid approach involving direct puncture of the main pulmonary artery (MPA) was used.
  • An Amplatzer Duct Occluder was implanted under transesophageal echocardiography guidance.
  • The MPA was accessed via a minimally invasive left parasternal incision.

Main Results:

  • PDA closure was successful in all six pediatric patients.
  • No residual shunts were detected immediately post-procedure or during midterm follow-up.
  • The procedure was associated with no hospital deaths and an uneventful postoperative course.

Conclusions:

  • The hybrid approach using an Amplatzer Duct Occluder is a safe and minimally invasive option for PDA closure.
  • Further studies with longer follow-up are needed to confirm its applicability in all PDA cases.
Abstract

Keywords:
Amplatzer Duct Occluderhybrid approachpatent ductus arteriosus

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