Related Experiment Video
Updated: Feb 5, 2026

26:41
Perspectives on Neuroscience
Published on: July 31, 2007
5.3K
The Life Sciences Translational Challenge: The European Perspective
Richard W Barker1, Jack W Scannell1
11 Centre for the Advancement of Sustainable Medical Innovation, Radcliffe Department of Medicine, Oxford University, Oxford, UK.
Therapeutic Innovation & Regulatory Science
|September 18, 2018
Summary
Life sciences research and development face sustainability challenges, particularly in Europe. This analysis examines European biopharmaceutical innovation, current actions, and future strategies to improve treatment translation.
Area of Science:
- Life Sciences
- Pharmaceuticals
- Biotechnology
Background:
- Traditional R&D models are increasingly unsustainable.
- Declining productivity in pharmaceutical R&D is a global concern.
- Lengthy and costly clinical development yields marginal patient benefit.
Purpose of the Study:
- Analyze challenges in European life sciences R&D.
- Examine factors impeding biopharmaceutical innovation in Europe.
- Identify current and suggest future actions for Europe.
Main Methods:
- Analysis of European biopharmaceutical innovation.
- Review of existing European initiatives.
- Identification of barriers and opportunities.
Main Results:
- European life sciences face unique hurdles in translating biological insights into treatments.
- Current European actions are underway to address R&D inefficiencies.
- Further strategic interventions are required.
Conclusions:
- Addressing specific European challenges is crucial for sustainable biopharmaceutical innovation.
- A multi-faceted approach is needed to enhance R&D productivity and patient benefit.
- Continued analysis and strategic action are vital for European life sciences.
Related Concept Videos
Half-life of a Reaction
39.1K
The half-life of a reaction (t1/2) is the time required for one-half of a given amount of reactant to be consumed. In each succeeding half-life, half of the remaining concentration of the reactant is consumed. For example, during the decomposition of hydrogen peroxide, during the first half-life (from 0.00 hours to 6.00 hours), the concentration of H2O2 decreases from 1.000 M to 0.500 M. During the second half-life (from 6.00 hours to 12.00 hours), the concentration decreases from 0.500 M to...
39.1K
Translation
156.6K
Lesson: Translation
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of...
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of...
156.6K
Psychology as a Science
3.9K
Psychology, as a scientific discipline, aims to understand the mind and behavior through rigorous and systematic methods. The foundation of psychological research is evidence-based, relying heavily on the scientific method to derive and validate knowledge. This structured approach ensures that findings are reliable, valid, and applicable to broader contexts.
The scientific method in psychology involves six critical steps: making observations, formulating hypotheses, conducting tests, analyzing...
The scientific method in psychology involves six critical steps: making observations, formulating hypotheses, conducting tests, analyzing...
3.9K
Characteristics of Life
261.6K
Biology is a natural science that studies life and living organisms, including their structure, function, development, interactions, evolution, distribution, and taxonomy. The field's scope is extensive and divided into several specialized disciplines, such as anatomy, physiology, ethology, genetics, and many more. All living things share a few key traits, including cellular organization, heritable genetic material and the ability to adapt/evolve, metabolism to regulate energy needs, the...
261.6K
The Angiosperm Life Cycle
72.6K
Plants have a life cycle split between two multicellular stages: a haploid stage—with cells containing one set of chromosomes—and a diploid stage—with cells containing two sets of chromosomes. The haploid stage is the gamete-producing gametophyte, and the diploid stage is the spore-producing sporophyte.
72.6K
Initiation of Translation
39.0K
Initiating translation is complex because it involves multiple molecules. Initiator tRNA, ribosomal subunits, and eukaryotic initiation factors (eIFs) are all required to assemble on the initiation codon of mRNA. This process consists of several steps that are mediated by different eIFs.
First, the initiator tRNA must be selected from the pool of elongator tRNAs by eukaryotic initiation factor 2 (eIF2). The initiator tRNA (Met-tRNAi) has conserved sequence elements including modified bases at...
First, the initiator tRNA must be selected from the pool of elongator tRNAs by eukaryotic initiation factor 2 (eIF2). The initiator tRNA (Met-tRNAi) has conserved sequence elements including modified bases at...
39.0K

