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Gender Differences in Outcomes Following a Pain-Free, Home-Based Exercise Program for Claudication
Roberto Manfredini1,2,3, Nicola Lamberti4, Fabio Manfredini3,4,5
1Department of Medical Sciences, University of Ferrara, Ferrara, Italy.
Journal of Women'S Health (2002)
|September 18, 2018
Summary
Home-based exercise programs for peripheral artery disease (PAD) show equal effectiveness for men and women. This pain-free walking program improved functional outcomes for both sexes, suggesting personalized home exercise is a viable option for PAD patients.
Area of Science:
- Cardiovascular Medicine
- Exercise Physiology
- Rehabilitation Science
Background:
- Peripheral artery disease (PAD) is a prevalent condition impacting patient mobility.
- Previous research indicated supervised exercise for claudication is less effective in women.
- This study examined sex-based differences in functional outcomes using a home-based exercise program for PAD.
Purpose of the Study:
- To retrospectively investigate sex differences in functional outcomes for PAD patients undergoing a pain-free, home-based exercise program.
- To compare the effectiveness of a structured home exercise regimen between male and female PAD patients.
Main Methods:
- Retrospective analysis of 1007 PAD patients (26% women) enrolled in a home-based program (2003-2016).
- Program involved daily pain-free walking sessions, with outcomes assessed at baseline and discharge.
- Key measures included pain threshold speed (PTS), maximal speed (Smax), pain-free walking distance (PFWD), 6-minute walk distance (6MWD), and ankle-brachial index (ABI).
Main Results:
- Women presented with lower baseline PTS and PFWD compared to men.
- Despite similar adherence rates, both sexes demonstrated comparable improvements in PTS, Smax, PFWD, 6MWD, and ABI post-program.
- Propensity analysis confirmed no significant between-group differences in functional outcome improvements.
Conclusions:
- A personalized, structured, pain-free home exercise program is equally effective for improving functional outcomes in both men and women with PAD.
- This approach, requiring minimal daily time, offers a viable treatment strategy for PAD patients.
- Future prospective studies should explore programs specifically designed to enhance adherence and functional outcomes in women with PAD.
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