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Related Concept Videos

Proteomics01:33

Proteomics

9.8K
A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
9.8K
Potential Energy00:52

Potential Energy

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The energy stored by a structure and location of matter in space is called potential energy. For instance, raising a kettlebell changes its spatial location and increases its potential energy. Similarly, a stretched rubber band contains potential energy which, under certain conditions, can be converted into other forms of energy, such as kinetic energy.
Chemical bonds that form attractive forces between atoms also contain potential energy, called chemical energy. When a chemical reaction...
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Potential Energy01:09

Potential Energy

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A conservative force, such as a gravitational or elastic force, gives the body the capacity to do work. This capacity, measured as the potential energy, depends on the body's location or “position” relative to a fixed reference position or datum. The gravitational potential energy is considered zero at the reference point. Suppose a body is located at some vertical distance above a fixed horizontal reference or datum. In that case, the weight of the body has positive gravitational potential...
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Standard Electrode Potentials03:02

Standard Electrode Potentials

50.4K
On comparing the reactivity of silver and lead, it is observed that the two ionic species, Ag+ (aq) and Pb2+ (aq), show a difference in their redox reactivity towards copper: the silver ion undergoes spontaneous reduction, while the lead ion does not. This relative redox activity can be easily quantified in electrochemical cells by a property called cell potential. This property is commonly known as cell voltage in electrochemistry, and it is a measure of the energy which accompanies the charge...
50.4K
Cell Potential and Free Energy02:58

Cell Potential and Free Energy

46.6K
Thermodynamics of a Redox Reaction
Thermodynamics is the branch of physics dealing with the relationship between heat and other forms of energy. In an electrochemical cell, chemical energy is converted into electrical energy.
Thus, a link can be predicted between cell potential, free energy change, and the equilibrium constant for the reaction. Cell potential can also be measured as the oxidant or the reducing strength, and similar acid-base strength measures are reflected in equilibrium...
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The Resting Membrane Potential01:21

The Resting Membrane Potential

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Overview
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Related Experiment Video

Updated: Feb 5, 2026

Quantification of the Potential Impact of Glyphosate-Based Products on Microbiomes
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Proteomics and the microbiome: pitfalls and potential.

Huafeng Lin1,2, Qing-Yu He3, Lei Shi2

  • 1a Department of Biotechnology , College of Life Science and Technology, Jinan University , Guangzhou , Guangdong , China.

Expert Review of Proteomics
|September 19, 2018
PubMed
Summary
This summary is machine-generated.

The human microbiome significantly impacts health and disease. Proteomics offers a powerful tool for analyzing the microbiome, identifying biomarkers, and advancing personalized medicine through a proteogenomics approach.

Keywords:
Fecal proteomicsbiomarkergenomicshuman microbiomepersonalized medicine

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Area of Science:

  • Microbiome research
  • Proteomics
  • Personalized medicine

Background:

  • Human symbiotic microbiota play crucial roles in health and disease.
  • Genomics, transcriptomics, and proteomics have advanced microbiome understanding.
  • The gut microbiome is central to gastrointestinal health.

Purpose of the Study:

  • To review the complexity of the microbiome and its health implications.
  • To discuss genomic and proteomic methods for microbiome analysis.
  • To outline the development of personalized medicine protocols.

Main Methods:

  • Metagenomics and proteomics for microbiome profiling.
  • Fecal proteomics for biomarker discovery and validation.
  • Development of clinically accepted assays and instrumentation.

Main Results:

  • Proteomics enables detailed protein profiling of the microbiome.
  • Fecal proteomics aids in identifying potential health and disease biomarkers.
  • Advancements support the development of personalized medicine.

Conclusions:

  • The microbiome's role in health and disease is increasingly recognized.
  • Proteomics is a key complementary method to metagenomics.
  • A proteogenomics approach is essential for understanding the microbiome network.