Related Experiment Video
Updated: Feb 5, 2026

A Screening Method for Identification of Heterochromatin-Promoting Drugs Using Drosophila
Published on: March 12, 2020
A convenient identification of carbamate-derived drug substances
Abstract:
The "second identification" of drugs in pharmacies and hospital pharmacies affords the availability of easy to perform and robust tests. Besides determination of melting points and simple chromatography (TLC), reliable color and precipitation reactions are common techniques for this purpose. Preferentially, these reactions allow for the identification of typical functional groups in the drugs. Here we present a reaction for identification of carbamate-type drugs, based on the precipitation of barium carbonate upon treating the analytes with barium hydroxide solution at 80 °C. This method works well for carbamate drugs with noteworthy water solubility like carbachol, neostigmine bromide, and pyridostigmine bromide, and could be considered as a method for second identification of these drugs in pharmacopoeias and in Deutscher Arzneimittel-Codex/Neues Rezeptur-Formularium (DAC-NRF).
Related Concept Videos
Convenience Sampling Method
Convenience sampling is a non-random method of sample selection; this method selects individuals that are easily accessible and may result in biased data. For example, a marketing...
Deleterious Substances in Aggregate
Another type of impurity is clay and fine material that...
Substance Use Disorders Affecting Sleep
Understanding the concepts of physical dependence,...
Measurement: Derived Units
Connective Tissue Fibers and Ground Substance
Higher Derivatives

