Intraoperative Blood and Coagulation Factor Replacement During Neurosurgery

Intraoperative blood and coagulation factor transfusion is of particular importance to neurosurgeons. Maintaining the hematologic and coagulation parameters of the patient within normal limits during surgery is critical to facilitate normal hemostasis, reduce transfusion requirements, and prevent complications associated with excessive blood loss. In this article, the authors review topics relevant to intraoperative transfusion during neurosurgery, including laboratory studies and other diagnostic modalities available to help with decision making, blood components and coagulation factors currently available for transfusion, and indications for intraoperative transfusion during cranial and spinal neurosurgical procedures.