Related Experiment Video
Updated: Feb 5, 2026
08:49
Models of Bone Metastasis
Published on: September 4, 2012
43.2K
[Bone epithelioid hemangioendotheliom]
K Grondin1, S Salomon1, H Sevestre2
1Service de rhumatologie, CHU Amiens-Picardie, place Victor Pauchet, 80054 Amiens cedex, France.
La Revue De Medecine Interne
|September 19, 2018
Summary
Epithelioid hemangioendothelioma (HHE) is a rare vascular tumor with unpredictable prognosis. This case highlights a fatal outcome in a 72-year-old man despite chemotherapy, underscoring the need for standardized treatments.
Area of Science:
- Oncology
- Pathology
- Vascular Biology
Background:
- Epithelioid hemangioendothelioma (HHE) is a rare mesenchymal neoplasm of vascular origin.
- It exhibits an epithelial-like appearance and can mimic angiosarcoma.
- The prognosis of HHE is variable and often unpredictable.
Observation:
- A 72-year-old male presented with inflammatory pain in the left lower limb.
- Radiographic imaging revealed multiple osteolytic lesions in the knee, tibia, medial malleolus, and calcaneus.
- Histological examination confirmed the diagnosis of HHE.
Findings:
- The patient received taxol chemotherapy.
- Despite treatment, the patient succumbed to the disease within 5 months.
- This case illustrates an aggressive clinical course of HHE.
Implications:
- There is a lack of standardized therapeutic guidelines for HHE.
- Further research is needed to establish effective treatment strategies for this rare cancer.
- Improved understanding of HHE pathogenesis may lead to better prognostic markers and targeted therapies.
Keywords:
Epithelioid hemagioendotheliomaHémangioendothéliome épithélioïdeMultiple myelomaMyélomePrimary bone tumorTumeur osseuse primitiveTumeur vasculaireVascular tumorMore Related Videos
06:53Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone
Published on: September 9, 2020
3.3K
08:41Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials
Published on: August 13, 2019
8.9K
Related Concept Videos
01:55Bone Structure
51.8K
Within the skeletal system, the structure of a bone, or osseous tissue, can be exemplified in a long bone, like the femur, where there are two types of osseous tissue: cortical and cancellous.
51.8K
01:40Bone Remodeling
40.5K
Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
40.5K
01:27Compact Bone
16.6K
Most bones contain compact and spongy osseous tissue, but their distribution and concentration vary based on the bone's overall function.
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...
16.6K
01:29Bone Disorders
5.4K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
5.4K
01:12The Hyoid Bone
5.1K
The hyoid bone is a small U-shaped bone located in the upper neck at the level of the inferior mandible, with its tips pointing posteriorly. It does not directly articulate with any other bone in the body. The hyoid acts as the attachment site for the tongue, the larynx, and the pharynx. It is held in position by a series of small muscles attached from above or below. These muscles help to move the hyoid up/down or forward/back in coordination with movements of the tongue, larynx, and pharynx...
5.1K
01:09Spongy Bone
7.9K
All bones comprise an outer layer of compact bone, and an interior made up of spongy bone tissue, also called cancellous or trabecular bone. In long bones, spongy bone tissue is mainly found in the interior of the epiphyses (broad ends of the bone).
Spongy bone is more porous, and less dense compared to compact bone. It is composed of concentric lamellae that are arranged irregularly to form the trabecular network. In some bones, the spaces between trabeculae contain red marrow, where...
Spongy bone is more porous, and less dense compared to compact bone. It is composed of concentric lamellae that are arranged irregularly to form the trabecular network. In some bones, the spaces between trabeculae contain red marrow, where...
7.9K