Related Experiment Video
Updated: Feb 5, 2026
09:33
MRI Mapping of Cerebrovascular Reactivity via Gas Inhalation Challenges
Published on: December 17, 2014
14.5K
Delivering Functional Imaging on the MRI-Linac: Current Challenges and Potential Solutions.
A Datta1, M C Aznar2, M Dubec3
1Department of Radiology, The Christie Hospital NHS Trust, Manchester, UK.
Clinical Oncology (Royal College of Radiologists (Great Britain))
|September 19, 2018
Summary
Magnetic resonance imaging (MRI) can map tumor microenvironment features for adaptive radiotherapy. This review explores challenges and solutions for implementing functional MRI on MRI-linear accelerators (linacs).
Area of Science:
- Oncology
- Radiotherapy
- Medical Imaging
Background:
- Magnetic resonance imaging (MRI) offers versatile tumor microenvironment assessment.
- Key features include cell death, proliferation, metabolism, angiogenesis, and hypoxia.
- These metrics hold potential for adaptive radiotherapy planning.
Purpose of the Study:
- To review challenges in implementing functional MRI on MRI-linear accelerators (linacs).
- To explore potential solutions for overcoming these challenges.
- To facilitate the integration of advanced MRI techniques into radiotherapy.
Main Methods:
- Literature review of functional MRI techniques.
- Analysis of challenges specific to MRI-linac integration.
- Discussion of proposed solutions and future directions.
Main Results:
- Functional MRI methods are established on diagnostic scanners.
- Significant technical and logistical hurdles exist for MRI-linac implementation.
- Potential solutions involve hardware modifications, advanced pulse sequences, and workflow optimization.
Conclusions:
- Integrating functional MRI with MRI-linacs is feasible but challenging.
- Addressing these challenges will enhance adaptive radiotherapy.
- Further research and development are needed for widespread clinical adoption.
Related Concept Videos
01:14Imaging Studies I: CT and MRI
894
Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
894
01:19Composition of Polyprotic Acid Solutions as a Function of pH
867
Polyprotic acids of the type H2M constitute two ionizable protons. As a result, on titration with a base, they exhibit two equivalence points in the titration curve. During titration, the species H2M, HM−, and M2− will be present in the solution at different points. The fractions of H2M, HM−, and M2− present at the various instances of the titration are denoted by α0, α1, and α2, respectively.
A graph with the alpha values is plotted against the volume of...
A graph with the alpha values is plotted against the volume of...
867
02:21Electrolyte and Nonelectrolyte Solutions
72.0K
Substances that undergo either a physical or a chemical change in solution to yield ions that can conduct electricity are called electrolytes. If a substance yields ions in solution, that is, if the compound undergoes 100% dissociation, then the substance is a strong electrolyte. Complete dissociation is indicated by a single forward arrow. For example, water-soluble ionic compounds like sodium chloride dissociate into sodium cations and chloride anions in aqueous solution.
72.0K
02:16Solution Formation
37.7K
There is no one solvent that can dissolve every type of solute. Some substances that readily dissolve in a certain solvent might be insoluble in a different solvent. A simple way to predict which substances dissolve in which solvent is the phrase "like dissolves like". This means that polar substances, such as salt and sugar, dissolve in a polar substance like water. In contrast, non-polar substances are more soluble in non-polar solvents such as carbon tetrachloride.
This selective...
This selective...
37.7K
02:24Ideal Solutions
22.5K
According to Raoult’s law, the partial vapor pressure of a solvent in a solution is equal or identical to the vapor pressure of the pure solvent multiplied by its mole fraction in the solution. However, Raoult's Law is only valid for ideal solutions. For a solution to be ideal, the solvent-solute interaction must be just as strong as a solvent-solvent or solute-solute interaction. This suggests that both the solute and the solvent would use the same amount of energy to escape to the...
22.5K
02:12General Properties of Solutions
35.8K
Many common substances around us exist as a solution, such as ocean water, air, and gasoline. All solutions are mixtures of substances that are composed of varying amounts of two or more types of atoms or molecules. A mixture with a non-uniform composition is a heterogeneous mixture, whereas a mixture with a uniform composition is a homogeneous mixture. The components that make the homogeneous mixture are evenly spread out and thoroughly mixed.
35.8K