Related Experiment Video
Updated: Feb 5, 2026

Partial Sciatic Nerve Ligation: A Mouse Model of Chronic Neuropathic Pain to Study the Antinociceptive Effect of Novel Therapies
Published on: October 6, 2022
Consensus-Based Treatment Approaches for Managing Concerning Behaviors in Patients on Long-term Opioid Therapy for
William C Becker1,2, E Jennifer Edelman2, Joanna L Starrels3
1VA Connecticut Healthcare System, New Haven, CT.
Abstract:
Guidelines recommend careful monitoring of patients on long-term opioid therapy for chronic pain to assess for concerning medication-taking behaviors that may signal opioid misuse or the presence of a substance use disorder. However, specific management strategies to guide providers if concerning medication-taking behaviors emerge are lacking. Therefore, we recruited a Delphi panel-42 experts in chronic pain and opioid prescribing-to develop consensus-based treatment approaches to guide management of the 6 most common and concerning behaviors identified: missing prescriber appointments, taking opioids for symptoms other than pain, using more opioid medication than prescribed, asking for an increase in opioid dose, aggressive behavior, and alcohol and other substance use. The results of that process are published as a separate study. The purpose of the present study was to present clinical cases in which concerning medication-taking behaviors arise in the course of long-term opioid therapy and demonstrate for readers how the Delphi panel's consensus-based approaches could be applied.
More Related Videos
Related Concept Videos
Analgesia and Pain Management
Behavior Therapy
Exposure therapy is a cornerstone of behavioral treatment for anxiety disorders. It involves systematic exposure to feared stimuli, either in real...
Opioid Analgesics: Synthetic and Semisynthetic Opioids
Rational Emotive Behavior Therapy
Lewis Acids and Bases
A coordinate covalent bond (or dative bond) occurs when one of the atoms in the bond provides both bonding electrons. For example, a coordinate covalent bond occurs when a water molecule combines with a hydrogen ion to form a hydronium ion. A coordinate covalent bond also results when...
Chronic Obstructive Pulmonary Disease-V: Management
Smoking Cessation

