Related Experiment Video
Updated: Feb 5, 2026

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
Published on: July 24, 2020
The role of optical coherence tomography and infrared oculography in assessing the visual pathway and CNS in multiple
Danko Coric1, Jenny A Nij Bijvank1,2, Laurentius J van Rijn2
1Department of Neurology, Amsterdam Neuroscience, VU University Medical Centre, Amsterdam, The Netherlands.
Abstract:
In this review, a current overview is provided of how optical coherence tomography and infrared oculography can aid in assessing the visual system and CNS in multiple sclerosis (MS). Both afferent and efferent visual disorders are common in MS and visual complaints can have a tremendous impact on daily functioning. Optical coherence tomography and infrared oculography can detect and quantify visual disorders with high accuracy, but could also serve as quantitative markers for inflammation, neurodegeneration and network changes including cognitive decline in MS patients. The assessment of the efferent and afferent visual pathways is relevant for monitoring and predicting the disease course, but is also potentially valuable as an outcome measure in therapeutic trials.
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