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Second-Order Circuits01:17

Second-Order Circuits

3.6K
Integrating two fundamental energy storage elements in electrical circuits results in second-order circuits, encompassing RLC circuits and circuits with dual capacitors or inductors (RC and RL circuits). Second-order circuits are identified by second-order differential equations that link input and output signals.
Input signals typically originate from voltage or current sources, with the output often representing voltage across the capacitor and/or current through the inductor. For example, in...
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First-Order Circuits01:15

First-Order Circuits

3.8K
First-order electrical circuits, which comprise resistors and a single energy storage element - either a capacitor or an inductor, are fundamental to many electronic systems. These circuits are governed by a first-order differential equation that describes the relationship between input and output signals.
One common example of a first-order circuit is the RC (resistor-capacitor) circuit. These circuits are used in relaxation oscillators such as neon lamp oscillator circuits. When voltage is...
3.8K
The Y-to-Y Circuit01:19

The Y-to-Y Circuit

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In a balanced four-wire wye-to-wye system, the arrangement involves wye-connected sinusoidal voltage sources and loads, connected through a neutral wire that links the neutral nodes of the source and load. The load impedance is connected across each phase of the load. The wye-connected source can be connected to the wye-connected load in four-wire and three-wire arrangements. A three-phase system is considered balanced when the load on each phase is equal, leading to uniform current flow and...
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LC Circuits01:21

LC Circuits

3.3K
An LC circuit consists of an inductor and a capacitor, either in series or parallel. Consider a charged capacitor connected with an inductor in series. Before the switch is closed, all the energy of the circuit is stored in the electric field of the capacitor. When the switch is closed, the capacitor begins to discharge, producing a current in the circuit. The current, in turn, creates a magnetic field in the inductor. Because of the induced emf in the inductor, the current cannot change...
3.3K
Role of Cerebellum and Prefrontal Cortex in Memory01:14

Role of Cerebellum and Prefrontal Cortex in Memory

1.2K
The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the...
1.2K
Levels of Organization01:09

Levels of Organization

141.0K
Biological organization is the classification of biological structures, ranging from atoms at the bottom of the hierarchy to the Earth's biosphere. Each level of the hierarchy represents an increase in complexity that builds upon the previous level.
Molecules Are Composed of Atoms, and Biomolecules Are Assembled from Molecules:
The most basic levels include atoms, molecules, and biomolecules. Atoms, the smallest unit of ordinary matter, are composed of a nucleus and electrons. Molecules...
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Related Experiment Video

Updated: Feb 5, 2026

Using Brain Activation nir-HEG/Q-EEG and Execution Measures CPTs in a ADHD Assessment Protocol
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Using Brain Activation nir-HEG/Q-EEG and Execution Measures CPTs in a ADHD Assessment Protocol

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Prefrontal circuit organization for executive control.

Tsukasa Kamigaki1

  • 1Department of Molecular and Cell Biology, Howard Hughes Medical Institute, University of California, Berkeley, CA 94720, United States.

Neuroscience Research
|September 19, 2018
PubMed
Summary
This summary is machine-generated.

The rodent prefrontal cortex (PFC) evaluates expected outcomes to select appropriate behaviors, inhibiting others. This involves distinct PFC subregions and local circuits, including VIP interneurons, for executive control.

Keywords:
Executive controlGABAergic interneuronMemory-guided behaviorPrefrontal cortexRodentTop-down signalVasoactive intestinal peptide (VIP)-positive interneuronWorking memory

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Area of Science:

  • Neuroscience
  • Cognitive Neuroscience
  • Systems Neuroscience

Background:

  • Executive control is crucial for selecting appropriate actions based on external stimuli and internal states.
  • The prefrontal cortex (PFC) is implicated in evaluating action outcomes and inhibiting competing behaviors.

Purpose of the Study:

  • To review evidence on how the rodent prefrontal cortex (PFC) implements executive control.
  • To explore the role of PFC subregions, recurrent networks, and local circuits in action selection.

Main Methods:

  • Review of empirical evidence implicating PFC function in executive control.
  • Overview of local circuit organization within the PFC, focusing on interneurons and neuromodulation.

Main Results:

  • The PFC evaluates and compares expected outcomes for candidate actions, selecting the most appropriate one.
  • Different PFC subregions contribute to distinct computational aspects via distributed networks.
  • Recurrent PFC networks integrate bottom-up signals over long timescales.
  • Vasoactive intestinal peptide-positive (VIP) interneurons modulate executive control signals.

Conclusions:

  • The disinhibitory module hypothesis proposes PFC organization where neuronal modules support executive control.
  • Distributed gain modulation, involving VIP neuron activity, adjusts ongoing executive control signals.