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siRNA Screening to Identify Ubiquitin and Ubiquitin-like System Regulators of Biological Pathways in Cultured Mammalian Cells
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A high content, small molecule screen identifies candidate molecular pathways that regulate rod photoreceptor outer

Leah J Campbell1,2, Megan C West1, Abbie M Jensen3,4

  • 1Biology Department, University of Massachusetts, Amherst, MA, 01003, USA.

Scientific Reports
|September 20, 2018
PubMed
Summary

This study identifies compounds regulating photoreceptor outer segment renewal, crucial for vision. The findings offer new insights into the molecular mechanisms governing the growth and shedding of these vital cellular structures.

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