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Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis
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Occupational allergic contact dermatitis caused by colophonium
Maria Pesonen1, Katri Suuronen1, Sari Suomela1
1Occupational Medicine, Finnish Institute of Occupational Health (FIOH), Helsinki, Finland.
Contact Dermatitis
|September 20, 2018
Summary
Occupational allergic contact dermatitis (OACD) from colophonium (rosin) is common in various jobs. Safety data sheets (SDSs) often lack crucial exposure information, making diagnosis challenging.
Area of Science:
- Dermatology
- Occupational Health
- Allergology
Background:
- Colophonium (rosin) is a frequent contact allergen found in both household and occupational environments.
- Occupational exposure to colophonium can lead to allergic contact dermatitis, impacting various industries.
Purpose of the Study:
- To identify common occupational sources of colophonium exposure.
- To determine which occupations are at higher risk for developing colophonium allergy.
- To evaluate the effectiveness of safety data sheets (SDSs) in assessing colophonium exposure.
Main Methods:
- Retrospective review of patch test data from 2002-2017 at the Finnish Institute of Occupational Health.
- Analysis of patch test results, occupation, and exposure details for 39 patients diagnosed with occupational allergic contact dermatitis (OACD) due to colophonium.
- Inclusion of patients tested for colophonium and abietic acid allergies.
Main Results:
- 4.6% of patients evaluated for occupational dermatitis showed positive reactions to colophonium.
- High-risk occupations included the wood industry, machining, soldering, and agriculture.
- Primary exposure sources were coniferous wood, wood-derived materials, glues, metalworking fluids, and soldering materials; SDSs were often inadequate or missing.
Conclusions:
- Occupational allergic contact dermatitis (OACD) from colophonium is prevalent across diverse occupations.
- Safety data sheets (SDSs) offer insufficient data for accurate colophonium exposure assessment.
- Utilizing patients' own materials for patch testing proved valuable for diagnosis.
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