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Updated: Feb 5, 2026

Validating Whole Genome Nanopore Sequencing, using Usutu Virus as an Example
Published on: March 11, 2020
[Usutu virus: the phantom menace]
Marion Clé1, Sara Salinas1, Sylvie Lecollinet2
1Pathogenesis and control of chronic infections, Université de Montpellier, Inserm, EFS, 60, rue de Navacelle, 34000 Montpellier, France.
Abstract:
Usutu virus, an arbovirus discovered in Africa in 1959, has spread over a large part of Europe over the last twenty years causing significant bird mortality as reported in France since 2015. The zoonotic risk, associated with this succession of avian epizootics in Europe, deserves to be taken into account even if human cases remain rare to date. Human infections are most often asymptomatic or present a benign clinical expression. However, neurological complications such as encephalitis or meningoencephalitis have been described. In addition, the recent description of an atypical case of facial paralysis in France suggests that the clinical spectrum of infections caused by Usutu virus is not fully characterized. Finally, the recent history of other arboviral outbreaks invites the scientific community to be extremely vigilant.
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