Related Experiment Video
Updated: Feb 5, 2026

Single-Anastomosis Duodeno-Ileal Bypass with Sleeve Gastrectomy Model in Mice
Published on: February 10, 2023
Lymphoscintigraphic Findings That Predict Favorable Outcome after Lymphaticovenous Anastomosis
1Division of Nuclear Medicine, Department of Radiology, Siriraj Hospital, Mahidol University. Bangkok, Thailand.
Radionuclide lymphoscintigraphy can predict successful lymphaticovenous anastomosis (LVA) outcomes. Dilated lymph vessels and dermal backflow on imaging indicate a favorable clinical result after LVA surgery for lymphedema.
Area of Science:
- Medical Imaging
- Vascular Surgery
- Lymphedema Management
Background:
- Lymphedema is a chronic condition characterized by fluid accumulation due to lymphatic system dysfunction.
- Lymphaticovenous anastomosis (LVA) is a surgical procedure to alleviate lymphedema by reconnecting lymphatic vessels to veins.
- Predicting surgical success in LVA is crucial for patient selection and management.
Purpose of the Study:
- To identify specific radiographic findings on pre-operative radionuclide lymphoscintigraphy that correlate with positive clinical outcomes after LVA.
- To evaluate the utility of lymphoscintigraphy in predicting the effectiveness of LVA for lymphedema treatment.
Main Methods:
- Retrospective review of 80 patients with upper or lower-limb lymphedema who underwent LVA.
- Analysis of pre-operative radionuclide lymphoscintigraphy findings, including dilated lymph vessels and dermal backflow.
- Correlation of lymphoscintigraphic results with clinical improvement observed post-LVA.
Main Results:
- Clinical improvement was noted in 50 out of 80 patients following LVA.
- The presence of dilated lymph vessels on lymphoscintigraphy was significantly associated with improved clinical outcomes.
- Dermal backflow observed during lymphoscintigraphy also showed a significant correlation with successful LVA results.
Conclusions:
- Radionuclide lymphoscintigraphy is a valuable tool for pre-operative assessment in LVA surgery.
- Identifying dilated lymph vessels and dermal backflow can help select patients likely to benefit from LVA.
- This imaging technique aids in optimizing treatment strategies for lymphedema patients.
Related Concept Videos
Predicting Reaction Outcomes
Gibbs Free Energy and Thermodynamic Favorability
Predicting Molecular Geometry
Finding the Center of Gravity
Outcomes of Glycolysis
Cellular respiration can occur aerobically (with oxygen) or anaerobically (without oxygen). In the presence of oxygen, cellular respiration starts with glycolysis and continues with pyruvate...
Respiratory System Abnormal Finding I: Inspection and Percussion
Inspection Findings
During an inspection, several findings may suggest the presence of respiratory distress or disease. Pursed-lip breathing, where exhalation is slowed by...

