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Adaptive Clinical Trials: Overview of Phase III Designs and Challenges

Jeff Maca1, Vladimir Dragalin2, Paul Gallo3

  • 11 Center for Statistics in Drug Development, Quintiles Inc, Morrisville, SC, USA.

Therapeutic Innovation & Regulatory Science
|September 21, 2018
PubMed

Keywords:
adaptive trial designconfirmatory studiesenrichment designsample size re-estimationseamless phase II/III

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