Sub-Diffraction Visible Imaging Using Macroscopic Fourier Ptychography and Regularization by Denoising
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Updated: Feb 5, 2026

Fourier-Based Diffraction Analysis of Live Caenorhabditis elegans
Published on: September 13, 2017
Zhixin Li1,2, Desheng Wen3, Zongxi Song4
1Xi'an Institute of Optics and Precision Mechanics, Chinese Academy of Sciences, Xi'an 710119, China. lizhixin2015@opt.cn.
Abstract:
Imaging past the diffraction limit is of significance to an optical system. Fourier ptychography (FP) is a novel coherent imaging technique that can achieve this goal and it is widely used in microscopic imaging. Most phase retrieval algorithms for FP reconstruction are based on Gaussian measurements which cannot extend straightforwardly to long range, sub-diffraction imaging setup because of laser speckle noise corruption. In this work, a new FP reconstruction framework is proposed for macroscopic visible imaging. When compared with existing research, the reweighted amplitude flow algorithm is adopted for better signal modeling, and the Regularization by Denoising (RED) scheme is introduced to reduce the effects of speckle. Experiments demonstrate that the proposed method can obtain state-of-the-art recovered results on both visual and quantitative metrics without increasing computation cost, and it is flexible for real imaging applications.
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