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Updated: Feb 5, 2026

Do-It-Yourself Device for Recovery of Cryopreserved Samples Accidentally Dropped into Cryogenic Storage Tanks
Published on: May 11, 2012
Comprehensive assessment of cryogenic storage risk and quality management concerns: best practice guidelines for ART
M C Schiewe1, M Freeman2, J B Whitney3
1Ovation Fertility, Newport Beach, CA, USA. mschiewe@ovationfertility.com.
Abstract:
Recent publicized events of cryogenic storage tank failures have created nationwide concern among infertility patients and patients storing embryos and gametes for future use. To assure patient confidence, quality management (QM) plans applied by in vitro fertilization (IVF) laboratories need to include a more comprehensive focus on the cryostorage of reproductive specimens. The purpose of this review is to provide best practice guidelines for the cryogenic storage of sperm, oocytes, embryos, and other reproductive tissues (e.g., testicular and ovarian tissue, cord blood cells, and stem cells) and recommend a strategy of thorough and appropriate quality and risk management procedures aimed to alleviate or minimize the consequences from catastrophic events.
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