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Updated: Feb 5, 2026

The In ovo CAM-assay as a Xenograft Model for Sarcoma
Published on: July 17, 2013
Propranolol for the treatment of vascular sarcomas
Michael J Wagner1,2, Lee D Cranmer1,2, Elizabeth T Loggers1,2
1Division of Medical Oncology, wagnermj@uw.edu.
Abstract:
Vascular sarcomas are abnormal proliferations of endothelial cells. They range from benign hemangioma to aggressive angiosarcoma, and are characterized by dysregulated angiogenic signaling. Propranolol is a β-adrenergic receptor inhibitor that has demonstrated clinical efficacy in benign infantile hemangioma, and is now being used experimentally for more aggressive vascular sarcomas and other cancers. In this review, we discuss the use of propranolol in targeting these receptors in vascular tumors and other cancers.
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