Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mismatch Repair01:36

Mismatch Repair

43.7K
Overview
43.7K
Mismatch Repair01:20

Mismatch Repair

6.6K
Organisms are capable of detecting and fixing nucleotide mismatches that occur during DNA replication. This sophisticated process requires identifying the new strand and replacing the erroneous bases with correct nucleotides. Mismatch repair is coordinated by many proteins in both prokaryotes and eukaryotes.
The Mutator Protein Family Plays a Key Role in DNA Mismatch Repair
The human genome has more than 3 billion base pairs of DNA per cell. Prior to cell division, that vast amount of genetic...
6.6K
Overview of DNA Repair02:25

Overview of DNA Repair

33.7K
In order to be passed through generations, genomic DNA must be undamaged and error-free. However, every day, DNA in a cell undergoes several thousand to a million damaging events by natural causes and external factors. Ionizing radiation such as UV rays, free radicals produced during cellular respiration, and hydrolytic damage from metabolic reactions can alter the structure of DNA. Damages caused include single-base alteration, base dimerization, chain breaks, and cross-linkage.
Chemically...
33.7K
Base Excision Repair01:54

Base Excision Repair

26.4K
One of the common DNA damages is the chemical alteration of single bases by alkylation, oxidation, or deamination. The altered bases cause mispairing and strand breakage during replication. This type of damage causes minimal change to the DNA double helix structure and can be repaired by the base excision repair (BER) pathways. BER corrects damaged DNA sequences by removing the damaged base and restoring the original base sequence using the complementary strand as a template.
The first step of...
26.4K
Nucleotide Excision Repair01:08

Nucleotide Excision Repair

40.9K
Overview
40.9K
Nucleotide Excision Repair01:38

Nucleotide Excision Repair

5.2K
DNA Distortion and Damage
Cells are regularly exposed to mutagens—factors in the environment that can damage DNA and generate mutations. UV radiation is one of the most common mutagens and is estimated to introduce a significant number of changes in DNA. These include bends or kinks in the structure, which can block DNA replication or transcription. If these errors are not fixed, the damage can cause mutations, which in turn can result in cancer or disease depending on which sequences are...
5.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Montecranon classification-a comprehensive treatment strategy for complex proximal ulna fracture dislocations.

JSES international·2025
Same author

Arthroscopic Treatment for Elbow Trauma: Learning Curve and Outcomes.

Hand clinics·2025
Same author

Clinical guideline on the open arthrolysis for post-traumatic elbow stiffness in adult patients.

Journal of shoulder and elbow surgery·2025
Same author

Efficacy of conservative treatment strategies for partial distal biceps tendon ruptures: a case-control study.

Journal of shoulder and elbow surgery·2025
Same author

The Use of the Procedure Room for Wide-Awake Local Anesthesia, No Tourniquet Hand Surgery in "High-Risk" Patients.

The Journal of hand surgery·2024
Same author

Revision radiocapitellar arthroplasty by mismatched implant components - A salvage option: A report of two cases with a minimum three-year follow-up.

Shoulder & elbow·2024
Same journal

Evans and Cotton Osteotomies Using Porous Titanium Wedges to Correct Pediatric Flatfoot Deformity.

JBJS essential surgical techniques·2026
Same journal

Biportal Endoscopic Posterior Cervical Foraminotomy.

JBJS essential surgical techniques·2026
Same journal

Five-Strand Hamstring Autograft Anterior Cruciate Ligament Reconstruction.

JBJS essential surgical techniques·2026
Same journal

Total Hip Replacement with Use of the French Paradox Cementing Technique for a Shortened Charnley-Kerboull Stem via a Bikini Approach.

JBJS essential surgical techniques·2026
Same journal

Pediatric Extra-Articular Proximal Femoral Fracture Fixation With a Submuscular Non-Locking Plate.

JBJS essential surgical techniques·2026
Same journal

Free Vascularized Fibular Grafting for Osteonecrosis of the Femoral Head.

JBJS essential surgical techniques·2026
See all related articles

Related Experiment Video

Updated: Feb 5, 2026

Murine Flexor Tendon Injury and Repair Surgery
07:32

Murine Flexor Tendon Injury and Repair Surgery

Published on: September 19, 2016

13.7K

Triceps Tendon Repair.

Megan Conti Mica1, Roger van Riet2

  • 1Department of Orthopedics, University of Chicago, Chicago, Illinois.

JBJS Essential Surgical Techniques
|September 21, 2018
PubMed
Summary
This summary is machine-generated.

Triceps tendon ruptures, often linked to anabolic steroid use, require prompt diagnosis and surgical repair for optimal outcomes. Early intervention improves the chances of successful direct repair and functional recovery.

More Related Videos

Author Spotlight: Advancing Tendon Research by Developing Mouse Assembloids to Understand Cellular Mechanisms
08:32

Author Spotlight: Advancing Tendon Research by Developing Mouse Assembloids to Understand Cellular Mechanisms

Published on: March 22, 2024

1.8K
Using Q Suture to Enhance Resistance to Gap Formation and Tensile Strength of Repaired Flexor Tendons
10:32

Using Q Suture to Enhance Resistance to Gap Formation and Tensile Strength of Repaired Flexor Tendons

Published on: June 3, 2020

6.3K

Related Experiment Videos

Last Updated: Feb 5, 2026

Murine Flexor Tendon Injury and Repair Surgery
07:32

Murine Flexor Tendon Injury and Repair Surgery

Published on: September 19, 2016

13.7K
Author Spotlight: Advancing Tendon Research by Developing Mouse Assembloids to Understand Cellular Mechanisms
08:32

Author Spotlight: Advancing Tendon Research by Developing Mouse Assembloids to Understand Cellular Mechanisms

Published on: March 22, 2024

1.8K
Using Q Suture to Enhance Resistance to Gap Formation and Tensile Strength of Repaired Flexor Tendons
10:32

Using Q Suture to Enhance Resistance to Gap Formation and Tensile Strength of Repaired Flexor Tendons

Published on: June 3, 2020

6.3K

Area of Science:

  • Orthopedic Surgery
  • Sports Medicine
  • Reconstructive Surgery

Background:

  • Triceps tendon ruptures can stem from trauma or chronic overuse leading to degeneration.
  • Anabolic steroid abuse is a significant predisposing factor, particularly in weightlifters.
  • Delayed diagnosis of triceps tendon ruptures is common, highlighting the need for thorough clinical evaluation.

Purpose of the Study:

  • To outline the diagnostic process for triceps tendon ruptures.
  • To detail the surgical technique for direct triceps tendon repair.
  • To discuss potential pitfalls and expected outcomes of triceps tendon repair surgery.

Main Methods:

  • Clinical examination is crucial for initial diagnosis.
  • Imaging modalities like ultrasound or MRI confirm ruptures.
  • Surgical repair involves debridement, anchor placement, and tendon suturing through bone tunnels.
  • Postoperative management includes splinting and progressive range of motion exercises.

Main Results:

  • Early diagnosis enhances the likelihood of successful direct repair.
  • Surgical repair aims for tension-free range of motion and functional strength.
  • Achieved outcomes include an average loss of 10° extension and flexion to 136°.
  • Peak strength at 1 year is approximately 80% of the uninjured side, with 99% endurance strength.

Conclusions:

  • Direct triceps tendon repair is indicated for full-thickness or large partial tears.
  • Challenges include differentiating scar tissue and potential need for grafts in chronic cases.
  • Rerupture rates can be up to 21%, emphasizing the importance of meticulous surgical technique and rehabilitation.