Related Experiment Video
Updated: Feb 5, 2026

Dynamic Measurement and Imaging of Capillaries, Arterioles, and Pericytes in Mouse Heart
Published on: July 29, 2020
Construction of Continuous Capillary Networks Stabilized by Pericyte-like Perivascular Cells
Kyoko Yamamoto1, Kohei Tanimura1, Masafumi Watanabe1
11 Department of System Design Engineering, Keio University, Yokohama, Japan.
Impact Statement:
Construction of capillary networks is a fundamental challenge for the development of three-dimensional (3D) tissue engineering. However, it is not well understood how to construct stable capillary networks that maintain a luminal size similar to that of capillary structures in vivo (i.e., <10 μm diameter). In this study, we demonstrated the construction of stable capillary networks covered by pericyte-like perivascular cells using an in vitro 3D angiogenesis model by optimizing interactions between endothelial cells and perivascular cells. Our 3D angiogenesis model can be combined with 3D culture of epithelial cells in the context of vascularization of 3D tissue-engineered constructs.
Related Concept Videos
BIBO stability of continuous and discrete -time systems
To determine the BIBO stability, the convolution integral is utilized when a bounded continuous-time input is applied to a Linear Time-Invariant (LTI) system....
Protein Networks
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
Network Covalent Solids
To break or to melt a covalent network solid, covalent bonds must be broken. Because covalent bonds are relatively strong, covalent network solids are typically...
Nuclear Stability
To hold positively charged protons together...
RNA Stability
Capillary Beds
Capillaries connect arterioles, small branches of arteries, to venules,...

