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Updated: Feb 5, 2026

Transaxillary First Rib Resection for Treatment of the Thoracic Outlet Syndrome
Published on: September 13, 2020
Thoracic Outlet Syndrome Treated With Injecting Botulinum Toxin Into Middle Scalene Muscle and Pectoral Muscle
Abed Rahman1, Albaraa Hamid, Konstantin Inozemtsev
1From the Department of Anesthesiology, John H. Stroger Cook County Hospital, Chicago, Illinois.
Thoracic outlet compression syndrome (TOS) can be effectively managed with targeted muscle injections. Botulinum toxin injections into the interscalene and pectoralis muscle planes offer significant symptomatic relief for TOS patients.
Area of Science:
- Pain Management
- Neurology
- Musculoskeletal Disorders
Background:
- Thoracic outlet compression syndrome (TOS) involves neurovascular compression at the superior thoracic aperture.
- TOS can occur in three distinct anatomical compartments: the interscalene triangle, costoclavicular space, and retropectoralis minor space.
Observation:
- A 44-year-old woman with TOS experienced treatment failure with conservative therapies, including physical therapy.
- The patient declined surgical intervention for her condition.
Findings:
- Injections into the middle interscalene muscle (ISM) and pectoralis muscle plane (PECS I and II) are increasingly utilized for TOS symptom relief.
- Successful treatment was achieved using ISM and PECS I/II blocks with botulinum toxin type A in the observed patient.
- Combined PECS I/II and ISM injections demonstrated excellent symptomatic relief.
Implications:
- Botulinum toxin injections represent a viable alternative for patients with TOS who are not candidates for or decline surgery.
- This minimally invasive approach offers significant symptomatic improvement for refractory TOS cases.
- Targeted muscle injections provide a promising therapeutic strategy for managing TOS.
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