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Updated: Feb 5, 2026

Minimal Erythema Dose MED Testing
Published on: May 28, 2013
Topical brimonidine-assisted laser treatment for the prevention of therapy-related erythema and hyperpigmentation
Sang Ju Lee1, Ga Ram Ahn2, Suk Bae Seo3
1Yonsei Star Skin & Laser Clinic , Seoul , Korea.
Abstract:
Postinflammatory hyperpigmentation (PIH) and erythema are the most common adverse effects associated with laser treatment, particularly in dark-skinned individuals. Several methods have been used to prevent or minimize these adverse effects; however, to date, no definitive precautions/strategies are known to prevent post-laser PIH and erythema. We investigated whether the topical application of the α-adrenergic receptor agonist brimonidine could reduce laser treatment-related complications such as erythema and PIH.
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