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Diurnal variations in recovery times after general anaesthesia in children

J Szolnoki1, D M Polaner1, T Eckle2

  • 1Department of Anaesthesiology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO, USA; Department of Anaesthesiology, Children's Hospital Colorado, Aurora, CO, USA.

British Journal of Anaesthesia
|September 22, 2018
PubMed

Insights

The time of day impacts pediatric recovery after general anesthesia for brain MRI. Longer post-anesthesia care unit (PACU) stays were observed later in the day for children over 3 years old.

Area of Science:

  • Anesthesiology
  • Pediatric Medicine
  • Chronobiology

Background:

  • Circadian rhythms influence physiological functions and disease development.
  • The impact of circadian rhythms on general anesthesia is not well understood.
  • Understanding anesthesia recovery times in children is crucial for optimizing care.

Purpose of the Study:

  • To investigate if the time of day affects pediatric recovery time after general anesthesia for brain MRI.
  • To determine if discharge readiness is influenced by the timing of anesthesia administration.

Main Methods:

  • Retrospective analysis of 2340 pediatric outpatient cases undergoing brain MRI.
  • Examined post-anesthesia care unit (PACU) length of stay.
  • Correlated PACU duration with time of day (morning vs. afternoon and specific time clusters).

Main Results:

  • Pediatric PACU stay significantly increased later in the day.
  • Children older than 3 or 5 years experienced maximum increases of 18-19 minutes in PACU stay.
  • This time-dependent increase was independent of sex, co-medications, or obstructive sleep apnea.

Conclusions:

  • The time of day significantly influences post-anesthesia recovery times in children undergoing brain imaging.
  • Children under 3 years may not experience this time-dependent effect.
  • Findings may inform strategies to shorten pediatric discharge times.
Abstract

Keywords:
ambulatory surgical proceduresanaesthesia, generalcircadian rhythmlength of staypaediatric anaesthesia

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