[Diagnosis and treatment of anal carcinoma]

Because of several different histological types of epithelium in the anal canal, various kinds of carcinomas such as adenocarcinoma, squamous carcinoma, cloacogenic carcinoma arise from this region, and carcinoma related to fistula in-ano is one of the characteristic malignancies. Though the fundamental treatment of anal carcinoma is rectal amputation, prophylactic gland dissection of inguinal lymph-node is not necessary except a case with definite metastasis. Numerous kinds of adjuvant chemotherapy to radical operation have been tried, however, selection of antitumor drugs, method of administration are not settled yet, and, at present, long term clinical effects are unknown.