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Updated: Feb 5, 2026

Novel Mini-open Transforaminal Lumbar Interbody Fusion
Published on: June 6, 2025
Transforaminal Lumbar Interbody Fusion (TLIF)
Jeffrey L Gum1, Deepak Reddy1, Steven Glassman1
1Norton Leatherman Spine Center, Louisville, Kentucky.
Transforaminal lumbar interbody fusion (TLIF) offers advantages over traditional posterior lumbar interbody fusion (PLIF) by minimizing dural retraction for improved outcomes. This technique facilitates better fusion success, decompression, and deformity correction in spinal fusion procedures.
Area of Science:
- Neurosurgery
- Orthopedic Surgery
- Spinal Fusion Techniques
Background:
- Posterior Lumbar Interbody Fusion (PLIF) historically used direct posterior approaches.
- Transforaminal Lumbar Interbody Fusion (TLIF) evolved to utilize a lateral access window, reducing dural retraction.
- TLIF theoretically offers enhanced fusion rates, foraminal decompression, deformity correction, and discogenic pain relief.
Purpose of the Study:
- To detail the procedural steps and considerations for Transforaminal Lumbar Interbody Fusion (TLIF).
- To highlight the technical nuances and advantages of the TLIF approach.
- To provide a systematic overview of TLIF for spinal fusion.
Main Methods:
- Standard posterior midline incision for spinal access.
- Pedicle screw placement followed by laminectomy and facetectomy for decompression.
- Disc space preparation via a lateral window, employing distraction techniques and specialized instruments for cage insertion and bone grafting.
Main Results:
- The described TLIF technique facilitates access to the interbody space with reduced dural tension.
- Thorough disc space preparation and appropriate cage selection are critical for fusion success and deformity correction.
- Postoperative recovery is comparable to other standard fusion procedures, with fusion expected within 6-12 months.
Conclusions:
- Transforaminal Lumbar Interbody Fusion (TLIF) is a viable alternative to PLIF, offering potential benefits in spinal fusion.
- Meticulous surgical technique, including distraction and disc space preparation, is key to successful TLIF outcomes.
- TLIF provides a comprehensive approach for treating various lumbar spine pathologies requiring fusion.
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