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Outcome Measures in Chronic Rhinosinusitis.

Fiona Ting1, Claire Hopkins1,2

  • 11ENT Department, Guy's Hospital, Great Maze Pond, London, SE1 9RT UK.

Current Otorhinolaryngology Reports
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Chronic rhinosinusitis (CRS) research needs standardized outcome measures. A proposed core outcome set aims to improve the value of studies on CRS interventions for adults.

Keywords:
Chronic rhinosinusitisCore outcome setsOutcome measuresOutcomesPROMs

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Area of Science:

  • Otolaryngology
  • Clinical Research Methodology

Background:

  • Chronic rhinosinusitis (CRS) significantly impacts patient quality of life and incurs substantial healthcare costs.
  • Current interventions for CRS are assessed using diverse objective and subjective outcome measures.
  • Heterogeneity in outcome measures hinders effective meta-analysis of existing research.

Purpose of the Study:

  • To review the currently available outcome measures for chronic rhinosinusitis.
  • To discuss the development and potential benefits of a core outcome set for CRS research.

Main Methods:

  • Literature review of existing objective and subjective outcome measures for CRS.
  • Analysis of the heterogeneity of current outcome measures.
  • Proposal for a standardized core outcome set.

Main Results:

  • A wide array of outcome measures are utilized in CRS research, with a growing emphasis on subjective patient-reported outcomes.
  • Significant heterogeneity exists among reported outcomes, limiting the synthesis of evidence.
  • A core outcome set is proposed to standardize reporting.

Conclusions:

  • Standardizing outcome measures through a core outcome set is crucial for enhancing the value and impact of future research on CRS interventions.
  • Implementing a core outcome set will facilitate more robust meta-analyses and improve clinical decision-making for adult CRS patients.