Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Protein Networks02:26

Protein Networks

4.6K
An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
4.6K
Protein Networks02:26

Protein Networks

2.9K
2.9K
Network Covalent Solids02:18

Network Covalent Solids

16.2K
Network covalent solids contain a three-dimensional network of covalently bonded atoms as found in the crystal structures of nonmetals like diamond, graphite, silicon, and some covalent compounds, such as silicon dioxide (sand) and silicon carbide (carborundum, the abrasive on sandpaper). Many minerals have networks of covalent bonds.
To break or to melt a covalent network solid, covalent bonds must be broken. Because covalent bonds are relatively strong, covalent network solids are typically...
16.2K
Network Function of a Circuit01:25

Network Function of a Circuit

712
Frequency response analysis in electrical circuits provides vital insights into a circuit's behavior as the frequency of the input signal changes. The transfer function, a mathematical tool, is instrumental in understanding this behavior. It defines the relationship between phasor output and input and comes in four types: voltage gain, current gain, transfer impedance, and transfer admittance. The critical components of the transfer function are the poles and zeros.
712
Sequence Networks of Rotating Machines01:24

Sequence Networks of Rotating Machines

489
A Y-connected synchronous generator, grounded through a neutral impedance, is designed to produce balanced internal phase voltages with only positive-sequence components. The generator's sequence networks include a source voltage that is exclusively in the positive-sequence network. The sequence components of line-to-ground voltages at the generator terminals illustrate this configuration.
Zero-sequence current induces a voltage drop across the generator's neutral impedance and other...
489
Inflammation01:38

Inflammation

62.1K
Overview
62.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Unique Hierarchical Mesostructures Arising from Biobased Double-Crystalline PLLA-<i>b</i>-PHDO-<i>b</i>-PLLA ABA Triblock Copolymers.

Biomacromolecules·2026
Same author

PLA/PCL Tubes Filled with Polysaccharide Hydrogels as Robust Hybrid Nerve Guidance Conduits with Controlled Swelling.

Macromolecular bioscience·2026
Same author

Optimizing toward Discovery: AI-Driven Exploration of Lewis Acid-Base Catalysts for PET Glycolysis.

Journal of the American Chemical Society·2026
Same author

NIR-Actuated Morphodynamic 2D Nanopatches for Interface-Programmed Immunoactivation and Tumor Regression.

Journal of the American Chemical Society·2026
Same author

Unveiling the Challenge of Evaporator Design in Clean Water Production Promoted by Superabsorbent Hydrogels and Sunlight.

ACS applied materials & interfaces·2026
Same author

Kinetically controlled hetero-fusion is a systems-level behaviour of polymer nanoparticle populations.

Nature communications·2025

Related Experiment Video

Updated: Feb 5, 2026

A Fabrication Method for Highly Stretchable Conductors with Silver Nanowires
07:50

A Fabrication Method for Highly Stretchable Conductors with Silver Nanowires

Published on: January 21, 2016

10.4K

Self-healing, stretchable and robust interpenetrating network hydrogels.

Laura J Macdougall1, Maria M Pérez-Madrigal2, Joshua E Shaw3

  • 1Department of Chemistry, University of Warwick, Coventry, CV4 7AL, UK.

Biomaterials Science
|September 22, 2018
PubMed
Summary

Researchers developed self-healing, stretchable hydrogels using polysaccharides and poly(ethylene glycol) (PEG). These biomaterials mimic the extracellular matrix (ECM) and maintain robust strength for regenerative medicine applications.

More Related Videos

Fragmenting Bulk Hydrogels and Processing into Granular Hydrogels for Biomedical Applications
10:18

Fragmenting Bulk Hydrogels and Processing into Granular Hydrogels for Biomedical Applications

Published on: May 17, 2022

6.8K
Scalable Fabrication of Stretchable, Dual Channel, Microfluidic Organ Chips
14:44

Scalable Fabrication of Stretchable, Dual Channel, Microfluidic Organ Chips

Published on: October 20, 2018

27.6K

Related Experiment Videos

Last Updated: Feb 5, 2026

A Fabrication Method for Highly Stretchable Conductors with Silver Nanowires
07:50

A Fabrication Method for Highly Stretchable Conductors with Silver Nanowires

Published on: January 21, 2016

10.4K
Fragmenting Bulk Hydrogels and Processing into Granular Hydrogels for Biomedical Applications
10:18

Fragmenting Bulk Hydrogels and Processing into Granular Hydrogels for Biomedical Applications

Published on: May 17, 2022

6.8K
Scalable Fabrication of Stretchable, Dual Channel, Microfluidic Organ Chips
14:44

Scalable Fabrication of Stretchable, Dual Channel, Microfluidic Organ Chips

Published on: October 20, 2018

27.6K

Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Polymer Chemistry

Background:

  • Self-healable and stretchable hydrogels are crucial for regenerative medicine.
  • Existing hydrogel systems often lack mechanical robustness or require complex synthesis.
  • Extracellular matrix (ECM) mimics require specific mechanical and self-healing properties.

Purpose of the Study:

  • To synthesize self-healing and stretchable poly(ethylene glycol) (PEG) interpenetrating networks (IPNs).
  • To utilize commercially available, unfunctionalized polysaccharides as a component.
  • To create ECM mimics with enhanced mechanical properties and translational applicability.

Main Methods:

  • Synthesis of poly(ethylene glycol) (PEG) based interpenetrating polymer networks (IPNs).
  • Incorporation of unfunctionalized polysaccharides into the hydrogel system.
  • Mechanical testing to evaluate compressive strength and stretchability.
  • Assessment of self-healing capabilities.

Main Results:

  • Successfully synthesized self-healing and stretchable PEG-based IPNs.
  • Maintained robust compressive strength (up to 2.4 MPa) comparable to PEG-only hydrogels.
  • Demonstrated the utility of unfunctionalized polysaccharides in enhancing hydrogel properties.
  • Achieved these properties without complex or costly natural polymer functionalization.

Conclusions:

  • Unfunctionalized polysaccharides can be readily incorporated into PEG hydrogels to create self-healing and stretchable materials.
  • These novel hydrogels serve as promising extracellular matrix (ECM) mimics for regenerative medicine.
  • The straightforward synthesis enhances the potential for clinical translation of these advanced biomaterials.