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Extubation in the Operating Room After Fontan Procedure: Does It Make a Difference?
Sebastian Kintrup1, Edward Malec1, Daniela Kiski2
1Division of Pediatric Cardiac Surgery, University Hospital Muenster, Albert-Schweitzer-Campus1-Geb.A1, 48149, Muenster, Germany.
Insights
Extubating children on the operating table after Fontan operation (FO) improved hemodynamics and reduced interventions compared to later extubation. This early extubation strategy in pediatric cardiac surgery shows significant benefits for early recovery.
Area of Science:
- Pediatric Cardiac Surgery
- Cardiovascular Physiology
- Critical Care Medicine
Background:
- The Fontan operation (FO) is a complex procedure for single ventricle heart malformations.
- Early extubation is hypothesized to benefit the Fontan circulation's early postoperative course.
Purpose of the Study:
- To compare the impact of intraoperative extubation versus early intensive care unit extubation on the early postoperative course following Fontan operation in children.
Main Methods:
- Retrospective analysis of pre-, peri-, and postoperative records of 114 children undergoing FO (2013-2016).
- Patients were divided into two groups: extubated in the operating room (ORE, n=60) and extubated in the intensive care unit (ICUE, n=54).
- Comparison of hemodynamic parameters, fluid balance, medication use, and metabolic status within the first 48 hours post-operation.
Main Results:
- The ORE group demonstrated lower heart rate and central venous pressure, and higher systolic blood pressure within 24 hours post-FO.
- ORE patients experienced significantly less pleural effusion, reduced intravenous fluid administration, and required less inotropic support and antibiotics.
- The ICUE group had a higher incidence of metabolic acidosis 3-4 hours post-FO.
Conclusions:
- Immediate extubation in the operating room following Fontan operation is associated with improved early hemodynamic stability.
- This strategy may lead to reduced therapeutic interventions, including fluid management, inotropic support, and antibiotic use.
- Intraoperative extubation appears to be a safe and beneficial approach for the early postoperative management of pediatric patients after Fontan operation.
Abstract:
Early extubation appears to have beneficial effects on the Fontan circulation. The goal of this study was to assess the impact of extubation on the operating table in comparison with extubation during the first hours after Fontan operation (FO) on the early postoperative course. Between 2013 and 2016, 114 children with a single ventricle heart malformations (mean age, 3.8 ± 2.3 years) underwent FO: 60 patients were extubated in the operating room (ORE) and 54 in the intensive care unit (ICUE) in the median time of 195 min (range 30-515 min) after procedure. Pre-, peri-, and postoperative records were retrospectively analyzed. The hospital survival rate was 100%. One patient from the ORE group needed an immediate reintubation because of laryngospasm. The ORE group showed lower heart rate (106.5 vs. 120.3 bpm; p < 0.001) and lower central venous pressure (10.4 vs. 11.4 mmHg; p = 0.001) than patients in the ICUE group within the first 24 h after FO, as well as higher systolic blood pressure within 7 h after operation (88.6 ± 2.5 vs. 85.6 ± 2.6 mmHg; p = 0.036). The ORE children manifested significantly less pleural effusions during 48 h after FO (38.0 vs. 49.5 ml/kg; p = 0.004), received less intravenous fluid administration within 24 h after FO (54.1 vs. 73.8 ml/kg; p = 0.019), less inotropic support (9.8 vs. 12.8 h of dopamine; p = 0.033), and less antibiotics (4.7 vs. 5.8 days; p = 0.037). ICUE children manifested metabolic acidosis more frequently than the ORE group 3-4 h after FO (p < 0.05). Immediate extubation after FO in comparison with extubation in the ICU appears to be associated with improved hemodynamics and reduced application of therapeutic interventions in the postoperative course.
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