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Updated: Aug 13, 2026

Chronic Salmonella Infection Induced Intestinal Fibrosis
Published on: September 22, 2019
Crohn's disease and cystic fibrosis: there is still a lot to learn
Claudio Trigo Salado1, Eduardo Leo Carnerero2, María Dolores de la Cruz Ramírez3
1Aparato Digestivo, 955012258, España.
Abstract:
The relationship between cystic fibrosis (CF) and the risk of developing inflammatory bowel disease (IBD) is not clear. CFTR mutations can influence dysbiosis and increased intestinal permeability, which are two key elements in the pathophysiology of IBD. These patients have increased intestinal inflammation, as demonstrated by increase pro-inflammatory gene expression in the bowel, specific fecal markers (fecal calprotectin), gross lesions (capsule endoscopy) and histological lesions on examination of surgical specimens.
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