Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Polymers

Polymers

The word polymer is derived from the Greek words “poly” which means “many” and “mer” which means “parts”. Polymers are long chains of molecules composed of repeating units of smaller molecules, known as monomers. They either occur naturally, such as DNA and proteins, or can be constructed synthetically, like plastics. They have varied structural characteristics, such as linear chains, branched chains, or complex networks, that contribute to the...

Polymers

Polymers

Dehydration Synthesis

Dehydration Synthesis

Overview
Dehydration synthesis (also called a condensation reaction) is the chemical process in which two molecules covalently link together to form a new molecule, along with the release of a water molecule. Many physiologically important compounds form by dehydration synthesis reactions, such as complex carbohydrates, proteins, DNA, and RNA.
Synthesis of carbohydrates
Sugar molecules are covalently linked together by dehydration synthesis. During the reaction, the hydroxyl (-OH) group from...

Transfer RNA Synthesis

Transfer RNA Synthesis

One of the unique features of tRNA is the presence of modified bases. In some tRNAs, modified bases account for nearly 20% of the total bases in the molecule. Altogether, these unusual bases protect the tRNA from enzymatic degradation by RNases.
Each of these chemical modifications is carried by a specific enzyme, post-transcription. All of these enzymes have unique base and site-specificity. Methylation, the most common chemical modification, is carried by at least nine different enzymes, with...

Lagging Strand Synthesis

Lagging Strand Synthesis

During replication, the complementary strands in double-stranded DNA are synthesized at different rates. Replication first begins on the leading strand. Replication starts later, occurs more slowly, and proceeds discontinuously on the lagging strand.
There are several major differences between synthesis of the leading strand and synthesis of the lagging strand. 1) Leading strand synthesis happens in the direction of replication fork opening, whereas lagging strand synthesis happens in the...

Cell Size

Cell Size

Cell sizes vary widely among and within organisms. Bacterial cells range between 1-10 micrometers (μm)and are considerably smaller than most eukaryotic cells. The smallest bacteria are 0.1 μm in diameter—about a thousand times smaller than eukaryotic cells, which typically range from 10-100 μm.
Surface Area
Cells can take in nutrients and water via diffusion through the plasma membrane itself or through specific channels in the membrane. The area of the membrane surrounding...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Functional Polyurethane Hydrogels for Cartilage Repair.

Biomacromolecules·2026

Same author

Uncovering Aggregation-Induced Emission in Carbon Dots for Color-Changing Hydrogels and Information Encryption.

Angewandte Chemie (International ed. in English)·2026

Same author

Alginate- and <i>κ</i>-carrageenan-supported asymmetric organocatalysts: preparation, characterization, and catalytic activity for Friedel-Crafts alkylation.

RSC advances·2025

Same author

Bipyridine-Containing Optically Active π-Conjugated Polymers Derived from Amino Alcohols: Examination of the Higher-Order Structures, Chiral Recognition, and Metal Coordination Based on Quantum Mechanical and Molecular Dynamics Calculations.

The journal of physical chemistry. A·2024

Same author

Cyclodextrin-based rotaxanes for polymer materials: challenge on simultaneous realization of inexpensive production and defined structures.

Beilstein journal of organic chemistry·2024

Same author

Exploring Catalytic Intermediates in Pd-Catalyzed Aerobic Oxidative Amination of 1,3-Dienes: Multiple Metal Interactions of the Palladium Nanoclusters.

Journal of the American Chemical Society·2024

Search research articles

Related Experiment Video

Updated: Feb 5, 2026

Nanosponge Tunability in Size and Crosslinking Density

Nanosponge Tunability in Size and Crosslinking Density

Published on: August 4, 2017

Cyclodextrin-Based [3]Rotaxane-Crosslinked Fluorescent Polymer: Synthesis and De-Crosslinking Using Size

Yosuke Akae¹, Hiromitsu Sogawa¹, Toshikazu Takata¹

¹Department of Chemical Science and Engineering, Tokyo Institute of Technology, 2-12-1, O-okayama, Meguro-ku, Tokyo, 152-8552, Japan.

Angewandte Chemie (International Ed. in English)

|September 22, 2018

Summary

This summary is machine-generated.

New rotaxane crosslinkers enable thermally reversible poly(methyl methacrylate) networks. This breakthrough allows for controlled de-crosslinking and material recycling, monitored by fluorescence.

Keywords:

cyclodextrins fluorescence polymers rotaxane crosslinked polymer supramolecular chemistry

More Related Videos

Fabricating Reactive Surfaces with Brush-like and Crosslinked Films of Azlactone-Functionalized Block Co-Polymers

Fabricating Reactive Surfaces with Brush-like and Crosslinked Films of Azlactone-Functionalized Block Co-Polymers

Published on: June 30, 2018

Synthesis of Stimuli-responsive Nanogels using Aqueous One-step Crosslinking and Co-nanopolymerization

Synthesis of Stimuli-responsive Nanogels using Aqueous One-step Crosslinking and Co-nanopolymerization

Published on: January 24, 2025

Related Experiment Videos

Last Updated: Feb 5, 2026

Nanosponge Tunability in Size and Crosslinking Density

Nanosponge Tunability in Size and Crosslinking Density

Published on: August 4, 2017

Fabricating Reactive Surfaces with Brush-like and Crosslinked Films of Azlactone-Functionalized Block Co-Polymers

Fabricating Reactive Surfaces with Brush-like and Crosslinked Films of Azlactone-Functionalized Block Co-Polymers

Published on: June 30, 2018

Synthesis of Stimuli-responsive Nanogels using Aqueous One-step Crosslinking and Co-nanopolymerization

Synthesis of Stimuli-responsive Nanogels using Aqueous One-step Crosslinking and Co-nanopolymerization

Published on: January 24, 2025

Area of Science:

Polymer Chemistry
Supramolecular Chemistry
Materials Science

Background:

Rotaxane-crosslinked polymers offer unique dynamic properties.
Controlling network integrity and reversibility is crucial for advanced materials.

Purpose of the Study:

To synthesize novel α-cyclodextrin-based rotaxane crosslinkers.
To create and characterize rotaxane-crosslinked poly(methyl methacrylate) (RCP).
To investigate the thermally induced de-crosslinking behavior of RCP.

Main Methods:

Synthesis of vinyl-group-substituted, α-cyclodextrin-based [3]rotaxanes.
Radical polymerization to form rotaxane-crosslinked poly(methyl methacrylate).
Monitoring de-crosslinking via fluorescence intensity changes.

Main Results:

Successful synthesis of size-complementary rotaxane crosslinkers.
Demonstrated thermally induced de-crosslinking of the RCP material.
Fluorescence intensity correlated with the degree of decoupling.

Conclusions:

The developed rotaxane crosslinkers enable the creation of thermally responsive polymer networks.
Size complementarity is key to achieving reversible crosslinking.
Fluorescence monitoring provides a viable method for assessing network disassembly.