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Moringa oleifera and their phytonanoparticles: Potential antiproliferative agents against cancer

Charlette Tiloke1, Krishnan Anand2, Robert M Gengan3

  • 1Discipline of Medical Biochemistry and Chemical Pathology, School of Laboratory Medicine and Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Private Bag 7, Congella, Durban, 4013, South Africa; Department of Chemistry, Faculty of Applied Sciences, Durban University of Technology, Durban, 4001, South Africa.

Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie
|September 22, 2018
PubMed

Insights

Moringa oleifera (MO) offers a natural approach to cancer treatment. Green synthesized gold phytonanoparticles from MO show potential as antiproliferative agents, improving cancer therapy outcomes.

Area of Science:

  • Phytomedicine
  • Nanotechnology
  • Oncology

Background:

  • Cancer remains a leading cause of mortality with conventional therapies causing severe side-effects.
  • Existing cancer treatments are often costly and inaccessible, necessitating innovative drug discovery.
  • Traditional medicine utilizes natural resources like Moringa oleifera (MO) for treating various ailments, including cancer.

Purpose of the Study:

  • To review the potential of Moringa oleifera (MO) in natural medicine.
  • To explore the green synthesis of gold phytonanoparticles using MO.
  • To highlight MO's role as an antiproliferative agent in cancer therapy.

Main Methods:

  • Literature review on Moringa oleifera's medicinal properties.
  • Investigation of green synthesis methods for gold nanoparticles using plant extracts.
  • Analysis of studies on the anticancer efficacy of MO-derived phytonanoparticles.

Main Results:

  • Moringa oleifera contains bioactive constituents with demonstrated efficacy against cancer.
  • Green synthesis offers a sustainable method for producing gold nanoparticles using MO.
  • MO-derived gold phytonanoparticles exhibit antiproliferative effects against cancer cells.

Conclusions:

  • Moringa oleifera is a valuable natural resource for developing novel cancer therapies.
  • Green synthesized gold phytonanoparticles from MO present a promising avenue for cancer treatment.
  • These phytonanoparticles may improve survival rates and quality of life for cancer patients.
Keywords:
AntiproliferativeApoptosisCancerGold phytonanoparticlesMoringa oleifera

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