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Intravascular Catheter-Related Bloodstream Infections

Mark E Rupp1, Rajendra Karnatak1

  • 1Division of Infectious Diseases, University of Nebraska Medical Center, 985400 Nebraska Medical Center, Omaha, NE 68198, USA.

Infectious Disease Clinics of North America
|September 23, 2018
PubMed

Insights

Catheter-related bloodstream infections (CRBSI) are a significant healthcare challenge. Effective prevention and treatment strategies are crucial for reducing patient harm and healthcare costs.

Area of Science:

  • Infectious Diseases
  • Clinical Medicine
  • Healthcare Management

Background:

  • Intravascular catheter-related bloodstream infections (CRBSI) persist as a major clinical issue.
  • CRBSI leads to substantial patient morbidity, mortality, and increased healthcare expenditures.

Purpose of the Study:

  • To outline essential strategies for the prevention and treatment of CRBSI.
  • To emphasize the importance of protocols and technological advancements in CRBSI management.

Main Methods:

  • Review of current clinical practices and guidelines for CRBSI prevention.
  • Analysis of diagnostic and therapeutic approaches for established CRBSI.
  • Evaluation of antimicrobial lock therapy for catheter salvage.

Main Results:

  • Prevention necessitates meticulous attention to insertion/maintenance protocols.
  • Technological innovations play a role in CRBSI prevention.
  • Treatment requires accurate diagnosis, appropriate antimicrobials, and often device removal.

Conclusions:

  • Comprehensive strategies encompassing prevention and treatment are vital for combating CRBSI.
  • Antimicrobial lock therapy is a key consideration for catheter salvage in select patients.
  • Addressing CRBSI effectively improves patient outcomes and reduces economic burden.

Keywords:
BacteremiaCatheter-related bloodstream infectionCentral line–associated bloodstream infectionCentral venous catheterHealth care–associated infection

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