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Hepatic tumors: US contrast enhancement with CO2 microbubbles
Radiology
|December 1, 1986
Summary
Carbon dioxide microbubbles enhance liver tumor visualization on sonograms. This diagnostic tool aids in differentiating hepatocellular carcinomas, metastatic tumors, and specific lesions like hemangiomas and granulomas.
Area of Science:
- Radiology
- Hepatology
- Oncology
Background:
- Liver tumors require accurate diagnostic methods.
- Contrast-enhanced ultrasonography offers potential for improved tumor characterization.
Purpose of the Study:
- To evaluate the efficacy of carbon dioxide microbubbles for enhanced ultrasonography of hepatic tumors.
- To classify enhancement patterns and correlate them with specific tumor types.
Main Methods:
- 43 patients with confirmed hepatic tumors underwent enhanced ultrasonography.
- Carbon dioxide microbubbles were injected into the hepatic artery as contrast.
- Sonograms were analyzed for five distinct enhancement patterns.
Main Results:
- Hepatocellular carcinomas predominantly showed hyperechoic changes (88%).
- Metastatic tumors frequently exhibited hypoechoic change with a rim sign (70%).
- Specific patterns identified cavernous hemangiomas and fibrous granulomas.
Conclusions:
- Enhanced ultrasonography with carbon dioxide microbubbles is effective for liver tumor assessment.
- This technique aids in differentiating tumor types and detecting small liver nodules.