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Related Experiment Videos

Hypervascular hepatic metastases: CT evaluation.

E L Bressler, M B Alpern, G M Glazer

    Radiology
    |January 1, 1987
    PubMed
    Summary
    This summary is machine-generated.

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    Non-contrast computed tomographic (CT) scans are valuable for detecting hypervascular liver metastases. Some metastases become indistinguishable from liver tissue after contrast enhancement, underscoring the need for non-contrast CT.

    Area of Science:

    • Radiology
    • Oncology

    Background:

    • Computed tomographic (CT) evaluation of hepatic metastases often relies on contrast-enhanced studies.
    • The utility of non-contrast material-enhanced scans versus contrast-enhanced studies for hepatic metastases requires further investigation.

    Purpose of the Study:

    • To retrospectively review CT scans of patients with hypervascular liver metastases.
    • To determine if hypervascular liver metastases are likely to become isodense with the liver after contrast enhancement, necessitating non-contrast scanning.

    Main Methods:

    • Retrospective review of CT scans from 28 patients with proved liver metastases.
    • Inclusion criteria: metastases from carcinoid tumors, islet cell neoplasms, pheochromocytomas, or renal cell carcinoma.
    • Scans analyzed: non-contrast-enhanced and contrast-enhanced incremental dynamic CT.

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    Main Results:

    • Eleven of 28 patients (39%) had metastases with non-contrast liver-to-lesion attenuation differences greater than 15 Hounsfield Units (HU).
    • These metastases became isodense or nearly isodense on contrast-enhanced scans.
    • This finding suggests a potential for missed detection with contrast-enhanced scans alone.

    Conclusions:

    • Non-contrast-enhanced CT scanning should be considered in patients with suspected liver metastases.
    • This approach is particularly relevant for tumors known to be hypervascular.
    • Non-contrast imaging can aid in the detection of metastases that may become isodense after contrast administration.