[Surgical treatment options for cervical paragangliomas]

Area of Science:

• Neuro-oncology
• Endocrinology
• Surgical Oncology

Background:

• Cervical paraganglioma (PG) is a rare tumor entity.
• Current therapies are evolving, necessitating a re-evaluation of treatment strategies.
• Tumor characteristics and patient factors influence therapeutic decisions.

Purpose of the Study:

• To outline the paradigm shift in cervical paraganglioma (PG) treatment.
• To discuss the risks and benefits of various therapeutic options.
• To emphasize the importance of individualized, multidisciplinary treatment planning.

Main Methods:

• Review of current therapeutic strategies for cervical paraganglioma.
• Analysis of surgical risks, radiotherapy outcomes, and conservative management.
• Consideration of multidisciplinary factors in treatment selection.

Main Results:

• Surgical resection is optimal for small, malignant, or endocrine-active PGs.
• External radiotherapy offers comparable recurrence rates with lower morbidity.
• A 'wait and scan' approach is suitable for slow-growing or asymptomatic tumors.
• Multidisciplinary evaluation is crucial, considering tumor size, location, genetics, and patient condition.

Conclusions:

• Treatment for cervical paraganglioma is becoming increasingly individualized.
• External radiotherapy and conservative management are viable alternatives to surgery for select patients.
• A multidisciplinary approach ensures optimal patient outcomes and quality of life.