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Updated: Feb 4, 2026

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
Published on: July 19, 2019
Home-based, square-stepping exercise program among older adults with multiple sclerosis: results of a feasibility
Emerson Sebastião1, Edward McAuley2, Ryosuke Shigematsu3
1Department of Kinesiology and Physical Education, Northern Illinois University, DeKalb, United States.
A 12-week home-based Square-Stepping Exercise (SSE) program was feasible for older adults with multiple sclerosis (MS). This intervention showed potential for improving mobility and cognitive function in this population.
Area of Science:
- Neurology
- Rehabilitation Science
- Gerontology
Background:
- Older adults with multiple sclerosis (MS) face significant declines in cognition and mobility.
- Exercise rehabilitation strategies for this demographic are under-researched.
Purpose of the Study:
- To assess the feasibility and acceptability of a 12-week home-based Square-Stepping Exercise (SSE) program for older adults with MS.
- To explore preliminary efficacy of SSE on cognitive and mobility outcomes.
Main Methods:
- A randomized controlled trial (RCT) involving 26 older adults with mild-to-moderate MS disability.
- Intervention group: 12-week home-based SSE with monitoring. Control group: Minimal activity with attention.
- Feasibility assessed via process, resource, management, and scientific outcomes. Compliance tracked with pedometers.
Main Results:
- High completion rate (96%) and good compliance with the SSE program.
- Small-to-moderate effect sizes observed for mobility and cognitive variables in the SSE group.
- The study was completed within budget ($13,387.00 USD).
Conclusions:
- Home-based SSE is a feasible and acceptable intervention for older adults with MS.
- Preliminary evidence suggests SSE may positively impact cognition and mobility in this population.
- Further research into SSE efficacy for MS rehabilitation is warranted.
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