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Published on: January 12, 2018
Prevention of meconium obstruction in very low birth weight preterm infants
A J Solaz-García1, L Segovia-Navarro1, J L Rodríguez de Dios-Benlloch1
1Unidad de Cuidados Intensivos Neonatales, Servicio de Neonatología, Hospital Universitario y Politécnico La Fe, Valencia, España.
Insights
Conservative treatment effectively prevents meconium obstruction in very-low-birth-weight preterm infants. This approach successfully facilitated meconium expulsion, avoiding surgical intervention for these vulnerable newborns.
Area of Science:
- Neonatalogy
- Pediatric Surgery
- Gastroenterology
Background:
- Delayed meconium expulsion is a significant cause of bowel obstruction in extremely premature newborns (<28 weeks gestational age) weighing under 1500g.
- This condition poses a serious risk to the health and survival of very-low-birth-weight infants.
Purpose of the Study:
- To assess the effectiveness of conservative management strategies in preventing meconium-related bowel obstruction.
- To determine if non-surgical interventions can successfully resolve meconium impaction in preterm infants.
Main Methods:
- A retrospective descriptive study was conducted in a Neonatal Intensive Care Unit.
- The study included very-low-birth-weight preterm infants diagnosed with meconium obstruction between August 2016 and January 2017.
Main Results:
- Out of 42 infants studied, 57.1% passed meconium spontaneously.
- The remaining 42.9% received conservative treatments, including saline enemas (72.2%), acetylcysteine enemas (16%), and Gastrografin® (16%).
- Crucially, no infants in the study required surgical intervention for meconium obstruction.
Conclusions:
- Conservative treatment is an effective method for managing meconium obstruction in very-low-birth-weight preterm infants.
- Non-surgical approaches successfully promote meconium expulsion, highlighting their value in preventing the need for surgery.
Introduction:
Delayed meconium expulsion is a cause of bowel obstruction in the extremely premature newborn (<28 WGE) weighing less than 1500g at birth.
Objective:
To evaluate the efficacy of conservative treatment in the prevention of meconium obstruction in very-low-birt- weight preterm infants.
Method:
Descriptive and retrospective study performed at the Neonatal Intensive Care Unit of a tertiary level hospital. All very-low-birth-weight preterm infants who were born during the study period, from August 2016 to January 2017, and who had meconium obstruction were included.
Results:
A sample of 42 newborn infants was obtained. Regarding the expulsion of meconium, 57.1% of the sample spontaneously ejected meconium, while 42.9% received different treatments. Of these, 72.2% were treated with saline enemas, 16% with acetylcysteine enemas, 16% with Gastrografin® and none required surgical treatment.
Conclusion:
Conservative treatment seems to be an effective therapeutic measure for the prevention of meconium obstruction in very-low-birth-weight preterm infants since it achieved the expulsion of meconium without having to apply surgical treatment.
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