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Updated: Feb 4, 2026

A Comprehensive Procedure to Evaluate the In Vivo Performance of Cancer Nanomedicines
Published on: March 4, 2017
Recent Advances in Targeted Tumor Chemotherapy Based on Smart Nanomedicines
Si-Yong Qin1,2, Ai-Qing Zhang1, Xian-Zheng Zhang2
1School of Chemistry and Materials Science, South-Central University for Nationalities, Wuhan, 430074, China.
Abstract:
Efficacy and safety of chemotherapeutic drugs constitute two major criteria in tumor chemotherapy. Nanomedicines with tumor-targeted properties hold great promise for improving the efficacy and safety. To design targeted nanomedicines, the pathological characteristics of tumors are extensively and deeply excavated. Here, the rationale, principles, and advantages of exploiting these pathological characteristics to develop targeted nanoplatforms for tumor chemotherapy are discussed. Homotypic targeting with the ability of self-recognition to source tumors is reviewed individually. In the meanwhile, the limitations and perspective of these targeted nanomedicines are also discussed.
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