Intracerebral malignant fibrous histiocytoma: a light and electron microscopic study with immunohistochemistry

A 65-year-old man presented with a tumor within the right cerebral hemisphere. Biopsy showed a pleomorphic neoplasm which was diagnosed as a malignant fibrous histiocytoma only after immunohistochemical and electron microscopic examination. Full clinical and radiological investigation, including total body CAT scanning, failed to reveal any other deposits, and thus it is believed to have arisen in the brain. It is emphasised that this diagnosis could not have been reached had only conventional histological techniques been available.