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Updated: Feb 4, 2026

Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart
Published on: May 11, 2018
Hand-sewn trileaflet valve in the right ventricular outflow tract
Kazuhiko Ishimaru1, Kanta Araki2, Shigeru Sakamoto1
11 Department of Cardiovascular Surgery, Kanazawa Medical University, Ishikawa, Japan.
A novel surgical technique using a synthetic membrane successfully repaired pulmonary regurgitation in a young child. This method offers a feasible alternative when standard bioprosthetic valves are too large.
Area of Science:
- Cardiovascular Surgery
- Pediatric Cardiology
- Biomaterials Science
Background:
- Tetralogy of Fallot repair can lead to pulmonary regurgitation.
- Pulmonary valve replacement is often necessary but challenging in young children.
- Limited options exist for pediatric patients requiring pulmonary valve intervention.
Observation:
- A 4-year-old girl presented with significant pulmonary regurgitation post-Tetralogy of Fallot repair.
- Standard bioprosthetic valves were unsuitable due to the patient's small size.
- An alternative surgical approach was considered for valve reconstruction.
Findings:
- A hand-sewn trileaflet valve reconstruction was performed using an expanded polytetrafluoroethylene (ePTFE) membrane.
- This technique effectively addressed the pulmonary regurgitation.
- The ePTFE membrane provided a viable solution for valve replacement in a pediatric patient.
Implications:
- This surgical method presents a feasible alternative for pulmonary valve replacement in young children.
- Expanded polytetrafluoroethylene membrane reconstruction offers a potential solution for complex pediatric cardiac cases.
- Further research may explore the long-term durability and outcomes of this technique.
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