Neonatal fever: A puzzling case

S Bonnet Ducrot1, D Plantaz2, N Mathieu3

  • 1Neonatal Intensive Care Unit, Grenoble Alpes University, CS10217, Grenoble University Hospital, 38043 Grenoble, France.

Toxoplasmosis is a potentially serious fetal infection associated with maternal seroconversion of toxoplasmosis during pregnancy. Follow-up and treatment vary between different countries. We present a case of congenital toxoplasmosis with unusual physiopathology and symptomatology. The mother was immunized before the beginning of pregnancy but immunosuppressive treatments for Crohn disease maintained during the pregnancy could explain toxoplasmosis reactivation in the mother and congenital toxoplasmosis. The baby presented reversible B lymphopenia and hypogammaglobulinemia.