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Development of matrix metalloproteinase-13 inhibitors - A structure-activity/structure-property relationship study

Rita Fuerst1, Jun Yong Choi2, Anna M Knapinska3

  • 1Department of Chemistry, Scripps Florida, Jupiter, FL 33458, United States; Institute of Organic Chemistry, Graz University of Technology, 8010 Graz, Austria.

Bioorganic & Medicinal Chemistry
|September 26, 2018
PubMed
Abstract

Keywords:
In vitro and in vivo pharmacokineticsMatrix metalloproteinase 13Microsomal stabilityPermeabilitySolubilityStructure-activity relationshipStructure-property relationship

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