Infant Feeding and Weight Gain: Separating Breast Milk From Breastfeeding and Formula From Food
Meghan B Azad1,2,3, Lorena Vehling4,2, Deborah Chan4,2
1Departments of Pediatrics and Child Health and meghan.azad@umanitoba.ca.
Insights
Breastfeeding duration and exclusivity impact infant obesity risk. Supplementation with formula after the neonatal period, but not solids, is linked to higher body mass index z-scores.
Area of Science:
- Pediatrics
- Public Health
- Nutrition Science
Background:
- Breastfeeding is recognized for its health benefits, yet specific feeding practices and their association with infant obesity remain under-documented.
- Previous studies often lack detailed information on feeding methods, supplementation types, and in-hospital feeding practices.
Purpose of the Study:
- To investigate the relationship between various breastfeeding and supplementation practices and infant body mass index (BMI) z-scores (BMIzs) at 12 months.
- To examine how the method of milk feeding (direct breastfeeding vs. expressed milk vs. formula) and timing of supplementation influence infant adiposity.
Main Methods:
- Utilized data from the CHILD birth cohort, including maternal reports and hospital records for feeding practices.
- Measured infant weight and BMIzs at 12 months, controlling for maternal BMI and other potential confounders.
- Employed regression analyses to assess associations between feeding styles and BMIzs.
Main Results:
- 97% of 2553 mother-infant dyads initiated breastfeeding, with a median duration of 11.0 months.
- Exclusive direct breastfeeding at 3 months was associated with the lowest BMIzs. Partial breastfeeding, use of expressed milk, and exclusive formula feeding were linked to significantly higher BMIzs.
- Formula supplementation by 6 months was associated with increased BMIzs, while solid food supplementation was not. Brief in-hospital formula supplementation did not negatively impact BMIzs if exclusive breastfeeding was sustained for at least 3 months.
Conclusions:
- Breastfeeding demonstrates a dose-dependent inverse association with infant weight gain velocity and BMI.
- Feeding expressed breast milk from a bottle partially diminishes these protective effects.
- Formula supplementation after the neonatal period substantially weakens the protective association of breastfeeding against infant obesity.
Objectives:
Studies addressing breastfeeding and obesity rarely document the method of breast milk feeding, type of supplementation, or feeding in hospital. We investigated these practices in the CHILD birth cohort.
Methods:
Feeding was reported by mothers and documented from hospital records. Weight and BMI z scores (BMIzs) were measured at 12 months. Analyses controlled for maternal BMI and other confounders.
Results:
Among 2553 mother-infant dyads, 97% initiated breastfeeding, and the median breastfeeding duration was 11.0 months. Most infants (74%) received solids before 6 months. Among "exclusively breastfed" infants, 55% received some expressed breast milk, and 27% briefly received formula in hospital. Compared with exclusive direct breastfeeding at 3 months, all other feeding styles were associated with higher BMIzs: adjusted β: +.12 (95% confidence interval [CI]: .01 to .23) for some expressed milk, +.28 (95% CI: .16 to .39) for partial breastfeeding, and +.45 (95% CI: .30 to .59) for exclusive formula feeding. Brief formula supplementation in hospital did not alter these associations so long as exclusive breastfeeding was established and sustained for at least 3 months. Formula supplementation by 6 months was associated with higher BMIzs (adjusted β: +.25; 95% CI: .13 to .38), whereas supplementation with solid foods was not. Results were similar for weight gain velocity.
Conclusions:
Breastfeeding is inversely associated with weight gain velocity and BMI. These associations are dose dependent, partially diminished when breast milk is fed from a bottle, and substantially weakened by formula supplementation after the neonatal period.
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