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Updated: Feb 4, 2026
Long-term Live-cell Imaging to Assess Cell Fate in Response to Paclitaxel
Published on: May 14, 2018
Evaluation of the use of nab-paclitaxel and gemcitabine in clinical practice
Cristina Casanova-Martinez1, Elena Yaiza Romero-Ventosa1, Sonia González-Costas1
1Hospital Pharmacy Service, Estructura Organizativa de Gestión Integrada de Vigo - Hospital, Álvaro Cunqueiro, Vigo, Pontevedra, Spain.
Context:
Pancreatic cancer in a common tumor in our country for which there are various treatment alternatives.
Objective:
Evaluate the effectiveness and safety of nab-paclitaxel and gemcitabine in everyday clinical practice.
Settings And Design:
Observational, retrospective study at a tertiary university hospital.
Subjects And Methods:
We included patients diagnosed of metastatic or locally advanced pancreatic cancer that were being treated with nab-paclitaxel and gemcitabine. We recorded response, progression-free survival (PFS), and overall survival (OS) rates together with toxicities.
Statistical Analysis Used:
We used SPSS program for Windows. We conducted descriptive statistics using averages, medians, standard deviations or ranges, and percentages.
Results:
We included 15 patients. At 3 months, there were no complete responses; 20% showed partial responses, and in 60% of patients, the disease stabilized. The median PFS was 8.9 months and the OS was 9.6. The most important adverse reactions were neutropenia, fatigue, and nausea/vomiting.
Conclusions:
The treatment regimen leads to increased survival in these patients with an acceptable toxicity profile.
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